| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | (S,R,S)-Me-AHPC-amide-C3-alkyne Basic information |
| | (S,R,S)-Me-AHPC-amide-C3-alkyne Chemical Properties |
| Boiling point | 804.7±65.0 °C(predicted) | | density | 1.209±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 13.97±0.40(predicted) |
| | (S,R,S)-Me-AHPC-amide-C3-alkyne Usage And Synthesis |
| Uses | (S,R,S)-Me-AHPC-amide-C3-alkyne is an E3 ligase ligand-linker conjugate used for the synthesis of JWZ-5-13 (HY-161828)[1]. | | References | [1] Ji W, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7)[J]. European Journal of Medicinal Chemistry, 2024: 116613. DOI:10.1016/j.ejmech.2024.116613 |
| | (S,R,S)-Me-AHPC-amide-C3-alkyne Preparation Products And Raw materials |
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