- PROSCILLARIDIN A
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- $1.00 / 1KG
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2019-07-06
- CAS:466-06-8
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
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| | PROSCILLARIDIN A Basic information |
| Product Name: | PROSCILLARIDIN A | | Synonyms: | SCILLARENIN 3BETA-RHAMNOSIDE;3-beta-rhamnosido-14-beta-hydroxy-delta(sup4,20,22)-bufatrienolide;a-32686;bufa-4,20,22-trienolide,3-beta-((6-deoxy-alpha-l-mannopyranosyl)oxy)-14-hydr;caradrin;cardion;cardiovite;carmazon | | CAS: | 466-06-8 | | MF: | C30H42O8 | | MW: | 530.66 | | EINECS: | 207-370-4 | | Product Categories: | | | Mol File: | 466-06-8.mol |  |
| | PROSCILLARIDIN A Chemical Properties |
| Melting point | 233°C | | alpha | D20 -91.5° (CH3OH) | | Boiling point | 530.03°C (rough estimate) | | density | 1.33±0.1 g/cm3 (20 ºC 760 Torr) | | refractive index | 1.4900 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO: 100 mg/mL (188.45 mM) | | pka | 13.01±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic | | LogP | 2.480 |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 28-45 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | UK6650000 | | Toxicity | LD50 in male, female rats (mg/kg): 56, 76 orally (Goldenthal) |
| | PROSCILLARIDIN A Usage And Synthesis |
| Uses | cardiotonic | | Uses | antipsychotic | | Definition | ChEBI: Proscillaridin is an organic molecular entity. | | Brand name | Tradenal (Knoll). | | Biological Activity | Proscillaridin A, a cardiac glycoside, is an antiarrhythmic drug th at enhances DNMT inhibitors and HDAC inhibitors activity. Combination of decitabine with proscillaridin A produced profound gene expression reprogramming associated with down-regulation of 153 epigenetic regulators including SYMD3 and KDM8. Proscillaridin A was recently identified as a potent anti-HBV agent (IC50 = 7.2?nM). |
| | PROSCILLARIDIN A Preparation Products And Raw materials |
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