H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2

Request For Quotation
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: GL Biochem (Shanghai) Ltd  
Tel: 21-61263452 13641803416
Email: ymbetter@glbiochem.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Company Name: Chemsky（shanghai）International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Company Name: Cellmano Biotech Limited  
Tel: 0551-65326643 18156095617
Email: info@cellmano.com

H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 manufacturers
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Basic information
Product Name:H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2
Synonyms:HK-1, MOUSE;HK-1 (MOUSE, RAT);H2N-RSRTRQFYGLM-AMIDE;HEMOKININ 1 (MOUSE);HEMOKININ 1 (MOUSE, RAT);HEK-1, MOUSE;HEK-1 (MOUSE, RAT);ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
CAS:208041-90-1
MF:C61H100N22O15S
MW:1413.65
EINECS:
Product Categories:Tachykinin receptor
Mol File:208041-90-1.mol
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Structure
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Chemical Properties
density 1.48±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: soluble
pka9.82±0.15(Predicted)
form powder
color white
Water Solubility Soluble to 2 mg/ml in water
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Usage And Synthesis
UsesHemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
in vivo

Hemokinin 1 (mouse) (0.01-100 nmol/kg i.v., n=10) induces a dose-related hypotension that is maximal at the dose of 10 nmol/kg. For systolic blood pressure (SBP), the ED50 value is 0.2 nmol/kg (0.1-0.4 nmol/kg) for Hemokinin 1 (mouse). For diastolic blood pressure (DBP), the ED50 value is 0.1 nmol/kg (0.07-0.2 nmol/kg) for Hemokinin 1 (mouse). Hemokinin 1 (mouse) (0.1-100 nmol/kg, i.v.) induces a dose-related salivary secretion in atropine-pretreated rats[1].

IC 50NK1
References[1] Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan; 135(1): 266-274
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Preparation Products And Raw materials
Tag:H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2(208041-90-1) Related Product Information
H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 TFA salt Gly-Leu-Met-NH2 Anti-Mouse NK1.1 Antibody (PK136) AZD2624 SENKTIDE