H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2

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H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Products Intro: Product Name:Hemokinin 1 (mouse, rat)
CAS:208041-90-1
Purity:98% Package:1KG;10KG;50KG
Company Name: Cellmano Biotech Limited
Tel: 0551-65326643 18156095617
Email: info@cellmano.com
Products Intro: Product Name:Hemokinin 1 (mouse, rat) HK-1 (mouse, rat), HEK-1 (mouse, rat)
CAS:208041-90-1
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
CAS:208041-90-1
Purity:>=98% Package:1g;1USD
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Hemokinin 1 mouse
CAS:208041-90-1
Purity:>=95% Remarks:Please reach out to us for more information about custom solutions.
Company Name: Hangzhou Go Top Peptide Biotech
Tel: 0571-88211921
Email: sales1@gotopbio.com
Products Intro: Product Name:Hemokinin1(mouse,rat)
CAS:208041-90-1
Purity:98% HPLC、MS Package:1mg/ plastic bottle ,customer's requirement packaging also welcome

H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 manufacturers
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Basic information
Product Name:H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2
Synonyms:HK-1, MOUSE;HK-1 (MOUSE, RAT);H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2;H2N-RSRTRQFYGLM-AMIDE;HEMOKININ 1 (MOUSE);HEMOKININ 1 (MOUSE, RAT);HEK-1, MOUSE;HEK-1 (MOUSE, RAT)
CAS:208041-90-1
MF:C61H100N22O15S
MW:1413.65
EINECS:
Product Categories:Tachykinin receptor
Mol File:208041-90-1.mol
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Structure
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Chemical Properties
density 1.48±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: soluble
pka9.82±0.15(Predicted)
form powder
color white
Water Solubility Soluble to 2 mg/ml in water
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Usage And Synthesis
UsesHemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
in vivo

Hemokinin 1 (mouse) (0.01-100 nmol/kg i.v., n=10) induces a dose-related hypotension that is maximal at the dose of 10 nmol/kg. For systolic blood pressure (SBP), the ED50 value is 0.2 nmol/kg (0.1-0.4 nmol/kg) for Hemokinin 1 (mouse). For diastolic blood pressure (DBP), the ED50 value is 0.1 nmol/kg (0.07-0.2 nmol/kg) for Hemokinin 1 (mouse). Hemokinin 1 (mouse) (0.1-100 nmol/kg, i.v.) induces a dose-related salivary secretion in atropine-pretreated rats[1].

IC 50NK1
References[1] Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan; 135(1): 266-274
H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 Preparation Products And Raw materials
Tag:H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2(208041-90-1) Related Product Information
GLY-LEU-MET-NH2 ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT H-ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2