|
|
| | 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine Basic information |
| Product Name: | 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine | | Synonyms: | 1-O-HEXADECYL-2-O-(5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE;C16-20:5 PC;EICOSAPENTAENOYL PAF C-16;L-A-PHOSPHATIDYLCHOLINE, B-*(CIS-5,8,11,14,17-;1-O-Palmityl-2-(cis-5,8,11,14,17-eicosapentaenoyl)-sn-glycero-3-phosphocholine;L-α-Phosphatidylcholine, β-(cis-5,8,11,14,17-eicosapentaenoyl)-γ-O-hexadecyl;1-O-HEXADECYL-2-(5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-20:5 PC;1-O-hexadecyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine | | CAS: | 132196-28-2 | | MF: | C44H80NO7P | | MW: | 766.08 | | EINECS: | | | Product Categories: | | | Mol File: | 132196-28-2.mol |  |
| | 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine Chemical Properties |
| storage temp. | −20°C | | solubility | acidic PBS: <50 μg/ml (from Docosahexaenoy; basic PBS: <50 μg/ml (from Docosahexaenoy; DMF: >14.3 mg/ml (from Docosahexaen; DMSO: 1 mg/ml; Ethanol: >1.7 mg/ml (from Docosahexaeno; PBS pH 7.2: <50 μg/ml (from Docosahexaenoy | | form | Oil. | | pka | 1.172±0.50(predicted) | | Sensitive | Hygroscopic | | InChIKey | YHSSHPWVFALMBA-IARQOZKNSA-N | | SMILES | [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COCCCCCCCCCCCCCCCC)=O |
| Hazard Codes | F,Xi | | Risk Statements | 11-36/37/38 | | Safety Statements | 16-26-36 | | WGK Germany | WGK 3 | | HazardClass | 3 | | Hazard Classifications | Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3 |
| | 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine Usage And Synthesis |
| Description | 1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC can be formed by incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, as has been demonstrated using neutrophils from monkeys and humans fed a diet enriched in fish oils. 1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC can serve as a substrate for PAF C-16 formation by the remodeling pathway. | | Uses | 1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine is a phospholipid present in blood plasma and blood cells[1]. | | Definition | ChEBI: 1-hexadecyl-2-[(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl]-sn-glycero-3-phosphocholine is a phosphatidylcholine O-36:5 in which the alkyl and acyl groups specified at positions 1 and 2 are hexadecyl and (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl respectively. It is a phosphatidylcholine O-36:5 and a 2-acyl-1-alkyl-sn-glycero-3-phosphocholine. It is functionally related to an all-cis-5,8,11,14,17-icosapentaenoic acid. | | References | [1] Triggiani M,et al. Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor. J Immunol. 1990 Oct 1;145(7):2241-8. PMID:2118931 |
| | 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine Preparation Products And Raw materials |
|