(E)-2'-Deoxy-2'-(fluoromethylene) cytidine manufacturers
- Tezacitabine
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- $2550.00
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2026-04-21
- CAS:130306-02-4
- Purity:
- Supply Ability: 10g
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| | (E)-2'-Deoxy-2'-(fluoromethylene) cytidine Basic information |
| Product Name: | (E)-2'-Deoxy-2'-(fluoromethylene) cytidine | | Synonyms: | tezaciabine;Cytidine, 2'-deoxy-2'-(fluoromethylene)-, (2'E)-;2'-deoxy-2'-(fluoromethylene)-(2E)Cytidine;(E)-2'-Deoxy-2'-(fluoromethylene)cytidine;(E)-2'-Deoxy-2'-(fluoromethylene) cytidine | | CAS: | 130306-02-4 | | MF: | C10H12FN3O4 | | MW: | 257.22 | | EINECS: | | | Product Categories: | | | Mol File: | 130306-02-4.mol |  |
| | (E)-2'-Deoxy-2'-(fluoromethylene) cytidine Chemical Properties |
| Boiling point | 512.5±60.0 °C(Predicted) | | density | 1.71±0.1 g/cm3(Predicted) | | storage temp. | -80°C | | solubility | DMSO : 200 mg/mL (777.54 mM; Need ultrasonic) | | form | Solid | | pka | 12.50±0.60(Predicted) | | color | Off-white to light yellow |
| | (E)-2'-Deoxy-2'-(fluoromethylene) cytidine Usage And Synthesis |
| Uses | Tezacitabine is used in the synthesis of inhibitors of ribonucleoside diphosphate reductase. | | in vivo | Tezacitabine (100 mg/kg; intraperitoneal injection; daily; female nude mice) treatment inhibits tumor growth in HCT 116 tumor xenografts[2]. | Animal Model: | Female nude mice (7-9-week-old) injected with HCT 116 cells[2] | | Dosage: | 100 mg/kg | | Administration: | Intraperitoneal injection; daily; 14 days | | Result: | Inhibited tumor growth in HCT 116 tumor xenografts.
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| | (E)-2'-Deoxy-2'-(fluoromethylene) cytidine Preparation Products And Raw materials |
| Raw materials | Cytidine, 2'-deoxy-2'-[fluoro(tributylstannyl)methylene]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-, (2'Z)- (9CI)-->Cytidine, 2'-deoxy-2'-(fluoromethylene)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-, (2'E)- (9CI) |
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