3-Quinolinecarboxaldehyde, 6-broMo- manufacturers
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| | 3-Quinolinecarboxaldehyde, 6-broMo- Basic information |
| | 3-Quinolinecarboxaldehyde, 6-broMo- Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | Appearance | Light yellow to green yellow Solid | | InChI | InChI=1S/C10H6BrNO/c11-9-1-2-10-8(4-9)3-7(6-13)5-12-10/h1-6H | | InChIKey | PCHCYMZZDAUVQB-UHFFFAOYSA-N | | SMILES | N1C2C(=CC(Br)=CC=2)C=C(C=O)C=1 |
| | 3-Quinolinecarboxaldehyde, 6-broMo- Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 6-bromoquinoline-3-carbaldehyde from (6-bromoquinolin-3-yl)methanol: (6-bromoquinolin-3-yl)methanol (716 mg, 2.70 mmol) was dissolved in dichloromethane (9 mL), manganese dioxide (705 mg, 8.12 mmol) was added, and the reaction was stirred at 20°C for 2 days. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to afford the target product 6-bromoquinoline-3-carbaldehyde (577 mg, 63% yield). | | References | [1] Patent: WO2011/131741, 2011, A1. Location in patent: Page/Page column 92
[2] Patent: US2012/94976, 2012, A1. Location in patent: Page/Page column 58 |
| | 3-Quinolinecarboxaldehyde, 6-broMo- Preparation Products And Raw materials |
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