| Company Name: |
BOC Sciences |
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16314854226; +8616314854226 |
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AZD 8329 manufacturers
- AZD8329
-
- $84.00
-
2026-07-14
- CAS:1048668-70-7
- Purity: 99.31%
- Supply Ability: 10g
- AZD8329
-
- $84.00
-
2026-07-14
- CAS:1048668-70-7
- Purity: 99.31%
- Supply Ability: 10g
|
| | AZD 8329 Basic information |
| Product Name: | AZD 8329 | | Synonyms: | AZD 8329;XWBXJBSVYVJAMZ-UHFFFAOYSA-N;AZD 8329
(AZD8329);Benzoic acid, 4-[5-(1,1-dimethylethyl)-4-[(tricyclo[3.3.1.13,7]dec-2-ylamino)carbonyl]-1H-pyrazol-1-yl]-;4-(4-(Adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid | | CAS: | 1048668-70-7 | | MF: | C25H31N3O3 | | MW: | 421.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1048668-70-7.mol |  |
| | AZD 8329 Chemical Properties |
| Boiling point | 620.5±50.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 62.5 mg/mL (148.27 mM) | | form | Solid | | pka | 3.77±0.10(Predicted) | | color | White to off-white |
| | AZD 8329 Usage And Synthesis |
| Uses | AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1]. | | References | [1] Scott JS, et al. Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J Med Chem. 2012 Nov 26;55(22):10136-47. DOI:10.1021/jm301252n |
| | AZD 8329 Preparation Products And Raw materials |
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