| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
|
| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:Ponatinib-d8 CAS:1562993-37-6 Purity:95%HPLC Package:10MG;25MG;50MG;100MG Remarks:DCTI-A-363
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| Company Name: |
Artis Biotech Co. Ltd.
|
| Tel: |
18108108965 18108108965 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Ponatinib D8 CAS:1562993-37-6 Purity:98%HPLC Package:1mg;5mg;10mg;50mg
|
Ponatinib-d8 manufacturers
- Ponatinib-D8
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- $678.00
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2026-07-27
- CAS:1562993-37-6
- Purity:
- Supply Ability: 10g
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| | Ponatinib-d8 Basic information |
| Product Name: | Ponatinib-d8 | | Synonyms: | Ponatinib-d8;[2H8]-Ponatinib;AP24534 D8;Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-3-(trifluoromethyl)phenyl]-;D8-Ponatinib | | CAS: | 1562993-37-6 | | MF: | C29H27F3N6O | | MW: | 532.57 | | EINECS: | | | Product Categories: | | | Mol File: | 1562993-37-6.mol |  |
| | Ponatinib-d8 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: soluble; Methanol: soluble | | form | A solid | | color | White to light yellow |
| | Ponatinib-d8 Usage And Synthesis |
| Uses | Ponatinib-d8 is an isotope labelled compound of Ponatinib (P688250). Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. It is a COVID19-related research product. | | IC 50 | c-Kit: 12.5 nM (IC50); VEGFR2: 1.5 nM (IC50); FGFR1: 2.2 nM (IC50); PDGFRα: 1.1 nM (IC50) |
| | Ponatinib-d8 Preparation Products And Raw materials |
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