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| | N-(1-Pyrenyl)maleimide Basic information |
| | N-(1-Pyrenyl)maleimide Chemical Properties |
| Melting point | 235-237 °C(lit.) | | Boiling point | 438.82°C (rough estimate) | | density | 1.2310 (rough estimate) | | refractive index | 1.5180 (estimate) | | storage temp. | Refrigerator | | solubility | Soluble in chloroform, N,Ndimethylformamide, dimethyl sulfoxide, ethanol, methanol | | form | Solid | | pka | –1.21±0.20, most basic, temperature: 25°C | | color | Yellow needles;Gold needles | | Appearance | off white solid | | λmax | 338nm, 325nm (MeOH) | | BRN | 1542661 | | Major Application | Dendrimers; dye functionalized single-wall carbon nanotube (SWNT) conjugated polymer devices; photovoltaic cells; polymer-coated gold electrodes; fluorescent polymers; radio-fluorogenic gel; in sequencecontrolled polymerizations; rubber | | Biological Applications | Analyzing molecular aspects of muscle contraction; detecting nucleic acids, proteins; determining/evaluating cell activity; diagnosing/treating Parkinson’s disease; monitoring/studying ribosomal structure and conformation; studying nicotinic acetylcholine receptor (AChR) structure; sulfhydryl reagent | | InChI | 1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H | | InChIKey | YXKWRQLPBHVBRP-UHFFFAOYSA-N | | SMILES | O=C1C=CC(=O)N1c2ccc3ccc4cccc5ccc2c3c45 | | CAS DataBase Reference | 42189-56-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 1 | | F | 8-10-21 | | HS Code | 29251900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | N-(1-Pyrenyl)maleimide Usage And Synthesis |
| Description | Pyrene is a fluorescent hydrocarbon which emits in blue region. This is a maleimide derivative of pyrenebutyric acid which reacts with thiols.
Pyrene is a useful proximity probe because two pyrene residues close to each other exhibit strong excimer fluorescence. | | Chemical Properties | N-(1-PYRENYL)MALEIMIDE is Yellow Solid | | Uses | Reactant used in synthesis of: • ;Oligodeoxynucleotide derivatives1 • ;Polymer conjugates of immunogenic peptides2 • ;Modified oligonucleotides for biosensing applications3,Reactant: • ;Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• ;Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5 | | Uses | N-(1-PYRENYL)MALEIMIDE is a fluorescent sulfhydryl reagent that can form excited-state dimers which emit at longer wavelenghts than the lone excited fluorophore. | | Abs/Em Maxima | 343; 326; 313; 276; 265; 242; 234/377; 397 nm |
| | N-(1-Pyrenyl)maleimide Preparation Products And Raw materials |
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