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| | DL-DECANOYLCARNITINE CHLORIDE Basic information |
| Product Name: | DL-DECANOYLCARNITINE CHLORIDE | | Synonyms: | (+/-)-DECANOYLCARNITINE CHLORIDE;DL-DECANOYLCARNITINE CHLORIDE;Decanoyl-L-carnitine chloride≥ 98% (TLC);(+/-)-Decanoylcarnitinechloride;(+/-)-Decanoylcarnit;(±)-Decanoylcarnitinechloride;(3-carboxy-2-decanoyloxypropyl)-trimethylazanium | | CAS: | 14919-36-9 | | MF: | C17H34ClNO4 | | MW: | 351.91 | | EINECS: | | | Product Categories: | Lipid signaling | | Mol File: | 14919-36-9.mol |  |
| | DL-DECANOYLCARNITINE CHLORIDE Chemical Properties |
| storage temp. | −20°C | | solubility | <35.19mg/ml in H2O | | form | solid | | color | White | | Water Solubility | Soluble to 100 mM in water |
| | DL-DECANOYLCARNITINE CHLORIDE Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Biological Activity | (±)-decanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-decanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3]. |
| | DL-DECANOYLCARNITINE CHLORIDE Preparation Products And Raw materials |
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