ChemicalBook > Product Catalog >Biochemical Engineering >Biochemical Reagents >Agonist Inhibitors >2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide

2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide

Request For Quotation
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: Shanghai JiYi Biotechnology Co. Ltd.  
Tel: 13621943973
Email: sales@shjiyipharmatech.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Shanghai QianYan Bio-technology Co., Ltd  
Tel: 02781293128
Email: orders@biochemsafebuy.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Basic information
Product Name:2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide
Synonyms:2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide;hnps-PLA Inhibitor;MDK-8582(Hnps-PLA Inhibitor);HNPS-PLA INHIBITOR; MDK-8582; MDK 8582; MDK8582;MDK 8582;MDK8582;MDK-8582;1H-Indole-3-acetamide, 4-(2-amino-2-oxoethoxy)-2-ethyl-α-oxo-1-(phenylmethyl)-
CAS:185298-58-2
MF:C21H21N3O4
MW:379.41
EINECS:
Product Categories:
Mol File:185298-58-2.mol
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Structure
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Chemical Properties
Melting point >230 °C
Boiling point 709.0±70.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
solubility DMSO: Sparingly soluble: 1-10 mg/ml
pka12.65±0.50(Predicted)
Safety Information
MSDS Information
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Usage And Synthesis
Useshnps-PLA-IN-1 (compound 5aa), a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM)[1].
References[1] Draheim SE, et al. Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. J Med Chem. 1996 Dec 20;39(26):5159-75. DOI:10.1021/jm960487f
[2] PHILIPPE BERNARD . A molecular modeling and 3D QSAR study of a large series of indole inhibitors of human non-pancreatic secretory phospholipase A2[J]. European Journal of Medicinal Chemistry, 2001, 36 1: Pages 1-19. DOI: 10.1016/s0223-5234(00)01183-1
2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Preparation Products And Raw materials
Tag:2-(4-(2-amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide(185298-58-2) Related Product Information
GDLMLQJISATCEL-UHFFFAOYSA-M FTY720 (R)-Phosphate (S) FTY720 PHOSPHATE racFTY720 Phosphate CAY10502 Neomycin sulfate