- Propargyl-PEG4-COOtBu
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2026-07-24
- CAS:1355197-66-8
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG4-t-butyl ester Basic information |
| Product Name: | Propargyl-PEG4-t-butyl ester | | Synonyms: | Propargyl-PEG4-t-butyl ester;Alkyne-PEG4-CH2CH2COOtBu;PROPARGYL-PEG4-CH2CH2COOTBU;Propargyl-PEG4-COOtBu;Propargyl-PEG4-Boc;4,7,10,13-Tetraoxahexadec-15-ynoic acid, 1,1-dimethylethyl ester;tert-butyl 4,7,10,13-tetraoxahexadec-15-ynoate;Propargyl-PEG4-t-Bu Ester | | CAS: | 1355197-66-8 | | MF: | C16H28O6 | | MW: | 316.39 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1355197-66-8.mol |  |
| | Propargyl-PEG4-t-butyl ester Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | Soluble in DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow |
| | Propargyl-PEG4-t-butyl ester Usage And Synthesis |
| Description | Propargyl-PEG4-t-butyl ester enables the formation of a stable triazole linkage with azide compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-butyl protected carboxyl group can be hydrolyzed under acidic conditions. | | Uses | Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG4-t-butyl ester Preparation Products And Raw materials |
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