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(R)-(-)-1-METHOXY-2-PROPANOL

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(R)-(-)-1-METHOXY-2-PROPANOL Basic information
Product Name:(R)-(-)-1-METHOXY-2-PROPANOL
Synonyms:2-Propanol, 1-Methoxy-,(2R)-;(R)-(-)-1-Methoxy-2-propanol;4-methoxy-3-(1-piperidinylmethyl)benzoic acid;(R)-2-HYDROXY-1-METHOXYPROPANE;(R)-(-)-1-METHOXY-2-PROPANOL;(R)-1-METHOXY-2-PROPANOL;(R)-(+)-PROPYLENE GLYCOL 1-METHYL ETHER;(R)-(-)-1-Methoxy-2-propanol, 98+%
CAS:4984-22-9
MF:C4H10O2
MW:90.12
EINECS:628-460-3
Product Categories:Chiral Compound;CHIRAL COMPOUNDS;chiral
Mol File:4984-22-9.mol
(R)-(-)-1-METHOXY-2-PROPANOL Structure
(R)-(-)-1-METHOXY-2-PROPANOL Chemical Properties
Melting point -97 °C
Boiling point 119-121 °C (lit.)
density 0.921 g/mL at 20 °C (lit.)
refractive index n20/D 1.403
Fp 33 °C
storage temp. Sealed in dry,2-8°C
form Liquid
pka14.49±0.20(Predicted)
color Clear colorless
Optical Rotation[α]20/D 22±2°, c = 10% in chloroform
BRN 1718941
InChIInChI=1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3/t4-/m1/s1
InChIKeyARXJGSRGQADJSQ-SCSAIBSYSA-N
SMILESC(OC)[C@H](O)C
CAS DataBase Reference4984-22-9(CAS DataBase Reference)
Safety Information
Hazard Codes F,Xn
Risk Statements 10-15
Safety Statements 24-43-7/8
RIDADR UN 3092 3/PG 3
WGK Germany 1
HazardClass 3
PackingGroup Ⅲ
HS Code 29051990
Storage Class3 - Flammable liquids
Hazard ClassificationsFlam. Liq. 3
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(R)-(-)-1-METHOXY-2-PROPANOL Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
Uses(R)-(-)-1-Methoxy-2-propanol can be used as a reactant to prepare:
  • (S)-3-(ethoxycarbonyl)-5-((1-methoxypropan-2-yl)oxy)benzoic acid, a key intermediate to synthesize phenylethyl benzamide derivatives, which can be used as glucokinase activators.
  • Chiral pyrazolopyrimidinone derivatives as potential phosphodiesterase enzyme (PDE5) inhibitors.
  • Aryl or alkyl ethers via etherification reaction.

General Description(R)-(-)-1-Methoxy-2-propanol is a chiral secondary alcohol. It is formed during the hydrolysis of (R)-1-methoxy-2-propyl-acetate in the presence of Candida antarctica lipase B.
(R)-(-)-1-METHOXY-2-PROPANOL Preparation Products And Raw materials
Raw materials(R)-(-)-2-Methoxypropanol-->(R)-1-Chloro-2-propanol-->Methanol-->(S)-(-)-Propylene oxide
Preparation Products(S)-(+)-1-Methoxy-2-propanol
Tag:(R)-(-)-1-METHOXY-2-PROPANOL(4984-22-9) Related Product Information
1-Ethoxy-2-propanol (R)-(-)-1-Amino-2-propanol (R)-(+)-Propylene carbonate (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol D-RIBULOSE 2,2'-Cyclouridine Digitoxin Reserpine RESCINNAMINE Clofibrate Ethyl 2-hydroxyisobutyrate DIGOXIN Methyl 2-hydroxyisobutyrate Methyl benzilate G-STROPHANTHIN CYMARIN (S)-(+)-1-METHOXY-2-PROPANOL 98%,(S)-1-METHOXY-2-PROPANOL,(S)-(+)-1-METHOXY-2-PROPANOL 1-Methoxy-2-propyl acetate