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| | Azido-PEG2-sulfonic acid Basic information |
| Product Name: | Azido-PEG2-sulfonic acid | | Synonyms: | Azido-PEG2-sulfonic acid;Azido-PEG2-C2-sulfonic acid;2-[2-(2-azidoethoxy)ethoxy]ethanesulfonic acid;2-(2-(2-Azidoethoxy)ethoxy)ethane-1-sulfonic acid;N3-PEG2-SO3H | | CAS: | 1817735-39-9 | | MF: | C6H13N3O5S | | MW: | 239.24952 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1817735-39-9.mol |  |
| | Azido-PEG2-sulfonic acid Chemical Properties |
| | Azido-PEG2-sulfonic acid Usage And Synthesis |
| Description | Azido-PEG2-sulfonic acid consist of an azide group and a sulfonic acid moiety. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. This reagent can support polypeptide synthesis, graft polymer compounds, PEG-modified functional coatings for new materials, etc. | | Uses | Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-sulfonic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG2-sulfonic acid Preparation Products And Raw materials |
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