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| | Amino-PEG3-sulfonic acid Basic information |
| Product Name: | Amino-PEG3-sulfonic acid | | Synonyms: | Amino-PEG3-sulfonic acid;Amino-PEG3-sulfonic acid HCl salt;Amino-PEG3-C2-sulfonic acid;Ethanesulfonic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-;Amino-PEG3-sulfonic acid hydrochloride | | CAS: | 1817735-43-5 | | MF: | C8H19NO6S | | MW: | 257.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1817735-43-5.mol |  |
| | Amino-PEG3-sulfonic acid Chemical Properties |
| density | 1.274±0.06 g/cm3(Predicted) | | solubility | Soluble in Water, DMSO, DMF | | pka | 1.34±0.50(Predicted) |
| | Amino-PEG3-sulfonic acid Usage And Synthesis |
| Description | Amino-PEG3-sulfonic acid HCl salt are PEG linkers containing an amine group and a sulfonic acid moiety. The amine group can react with carboxylic acids, activated NHS esters and other carbonyl groups. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. | | Uses | Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | Amino-PEG3-sulfonic acid Preparation Products And Raw materials |
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