- STIMA-1
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- $30.00
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2026-05-11
- CAS:91634-12-7
- Purity: 99.37%
- Supply Ability: 10g
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| | 2-Vinyl-4-quinazolinol Basic information |
| Product Name: | 2-Vinyl-4-quinazolinol | | Synonyms: | 2-VINYL-3H-QUINAZOLIN-4-ONE;2-Vinylquinazolin-4(3H)-one;STIMA 1;4(3H)-Quinazolinone, 2-ethenyl-;2-vinylquinazolin-4(1H)-one;2-ethenyl-1H-quinazolin-4-one;2-Ethenyl-3,4-dihydroquinazolin-4-one;2-Vinylquinazolin-4-ol | | CAS: | 91634-12-7 | | MF: | C10H8N2O | | MW: | 172.18 | | EINECS: | | | Product Categories: | | | Mol File: | 91634-12-7.mol |  |
| | 2-Vinyl-4-quinazolinol Chemical Properties |
| Melting point | >200°C (dec.) | | Boiling point | 315.4±25.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 1.91±0.20(Predicted) | | color | White to Off-White | | Stability: | Light Sensitive | | InChI | 1S/C10H8N2O/c1-2-9-11-8-6-4-3-5-7(8)10(13)12-9/h2-6H,1H2,(H,11,12,13) | | InChIKey | VCHFWHQHIKFOIC-UHFFFAOYSA-N | | SMILES | n1c2c(c(nc1C=C)O)cccc2 |
| Hazard Codes | Xi | | WGK Germany | WGK 2 | | HazardClass | IRRITANT | | Storage Class | 11 - Combustible Solids |
| | 2-Vinyl-4-quinazolinol Usage And Synthesis |
| Uses | STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells[1]. | | References | [1] Nicole Zache, et al. Mutant p53 targeting by the low molecular weight compound STIMA-1. Mol Oncol. 2017 May;11(5):595. DOI:10.1002/1878-0261.12065 |
| | 2-Vinyl-4-quinazolinol Preparation Products And Raw materials |
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