2-METHYL-4(3H)-QUINAZOLINONE manufacturers
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| | 2-METHYL-4(3H)-QUINAZOLINONE Basic information |
| | 2-METHYL-4(3H)-QUINAZOLINONE Chemical Properties |
| Melting point | 231-233 °C(lit.) | | Boiling point | 286.07°C (rough estimate) | | density | 1.1846 (rough estimate) | | refractive index | 1.5570 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO : 50 mg/mL (312.17 mM; Need ultrasonic)| | | form | powder to crystal | | pka | 3.60±0.20(Predicted) | | color | White to Almost white | | Water Solubility | Water : < 0.1 mg/mL (insoluble) | | λmax | 316nm(CH3CN)(lit.) | | InChI | 1S/C9H8N2O/c1-6-10-8-5-3-2-4-7(8)9(12)11-6/h2-5H,1H3,(H,10,11,12) | | InChIKey | FIEYHAAMDAPVCH-UHFFFAOYSA-N | | SMILES | CC1=Nc2ccccc2C(=O)N1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | RTECS | VA3677000 | | HS Code | 2933.79.1500 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| | 2-METHYL-4(3H)-QUINAZOLINONE Usage And Synthesis |
| Uses | 2-Methyl-4(3H)-quinazolinone may be used in chemical synthesis. | | Synthesis Reference(s) | Journal of the American Chemical Society, 73, p. 5777, 1951 DOI: 10.1021/ja01156a085 The Journal of Organic Chemistry, 40, p. 144, 1975 | | in vivo | 2-Methylquinazolin-4-ol (0.2-1 mg; i.g.; for two days) inhibits ATCase in a dosedependent manner in vivo[2].
| Animal Model: | Mice[2] | | Dosage: | 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1 mg | | Administration: | Oral gavage, for two days | | Result: | Showed an inhibitory effect upon ATCase. |
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| | 2-METHYL-4(3H)-QUINAZOLINONE Preparation Products And Raw materials |
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