- Atomoxetine
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- $1520.00
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2026-05-11
- CAS:83015-26-3
- Purity:
- Supply Ability: 10g
- (R)-Tomoxetine
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- $2.00
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2020-01-08
- CAS:83015-26-3
- Min. Order: 1g
- Purity: 98%MIN
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| | (R)-Tomoxetine Basic information |
| Product Name: | (R)-Tomoxetine | | Synonyms: | n-methyl-3-(2-methylphenoxy)benzenepropanamine;(r)-tomoxetine;TomoxetineHcl;N-Methyl--(2-methylphenoxy)benzenepropanamine;N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine;(R)-N-Methyl-3-phenyl-3-(2-methylphenoxy)-1-propanamine;Methyl[(R)-3-phenyl-3-(2-methylphenoxy)propyl]amine;(-)-N-Methyl-3-(o-methylphenoxy)-3-phenylpropylamine | | CAS: | 83015-26-3 | | MF: | C17H21NO | | MW: | 255.36 | | EINECS: | 617-427-9 | | Product Categories: | Inhibitors;Pharmacetes & Fine Chemicalsuticals | | Mol File: | 83015-26-3.mol |  |
| | (R)-Tomoxetine Chemical Properties |
| | (R)-Tomoxetine Usage And Synthesis |
| Uses | (R)-Tomoxetine is a compound active at novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases. | | Definition | (R)-Tomoxetine is a secondary amino compound having methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents. | | Brand name | Strattera
(Lilly). | | in vivo | Atomoxetine (Tomoxetine) (0.3-3 mg/kg; i.p.; 0-4 hours; male Sprague-Dawley rats) increases extracellular norepinephrine and dopamine by 3-fold and increases Fos expression in the rat prefrontal cortex[1].
Atomoxetine (Tomoxetine) (0.1-5 mg/kg; i.p. and p.o; for 14 days; spontaneously hypertensive rat) can improve behaviors associated with ADHD in rats[3]. | Animal Model: | Male Sprague-Dawley rats[1] | | Dosage: | 0.3, 1 and 3 mg/kg | | Administration: | Intraperitoneal injection; for 4 hours | | Result: | Increased the number of cells expressing Fos-like immunoreactivity in PFC 3.7-fold and increased extracellular norepinephrine and dopamine by 3-fold. |
| Animal Model: | Spontaneously hypertensive rat (SHR)[3] | | Dosage: | 0.1, 0.3, 1.25 and 5.0 mg/kg | | Administration: | Intraperitoneal injection and oral administration; for 14 days | | Result: | Had non-impact on the measurement of motor activity. |
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| | (R)-Tomoxetine Preparation Products And Raw materials |
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