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| | PYRAZOPHOS Basic information |
| | PYRAZOPHOS Chemical Properties |
| Melting point | 51℃ | | density | 1.38±0.1 g/cm3(Predicted) | | vapor pressure | 2.2 x 10-4 Pa (50 °C) | | storage temp. | APPROX 4°C | | Water Solubility | 4.2 mg l-1 (25 °C) | | pka | -1.37±0.40(Predicted) | | Merck | 13,8052 | | BRN | 577209 | | EPA Substance Registry System | Pyrazophos (13457-18-6) |
| Hazard Codes | Xn,N | | Risk Statements | 20/22-50/53 | | Safety Statements | 36/37-46-60-61 | | RIDADR | 2783 | | WGK Germany | 3 | | RTECS | TF2035000 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 in rats, marmots, rabbits (mg/kg): 140, 184, 435 orally (Smit) |
| | PYRAZOPHOS Usage And Synthesis |
| Chemical Properties | Pure product is colorless crystals. m.p. 51~53℃, relative density 1.348 (25℃), vapor pressure >0.133×10-3Pa (20℃), 0.221×10-3Pa (50℃). solubility at 20℃: acetone 121.2%, toluene >98%, ethyl acetate 89.8%, ethanol 9.5%, hexane 1.1%, water 0.42% (0.03%). Also soluble in benzene, xylene, carbon tetrachloride, trichloroethylene and other organic solvents. It is easy to decompose under acidic and alkaline conditions, but it will not produce obvious decomposition phenomenon when stored under dry conditions for 2 years. | | Uses | Pyrazophos is an anticholinesterase pesticide used on fruits and vegetables and can be determined by gas chromatography/mass spectrometry and liquid chromatography with fluorescence detection. | | Uses | Fungicide. | | Uses | Pyrazophos is a systemic fungicide that provides both protective
and curative control of various fungal diseases such as powdery mildew
(Podosphaera) on apples, stone fruits, bush fruits and strawberries,
Erysiphe in cucurbits and tomatoes, Uncinula on vines and leaf blotch
(Rhynchosporium) in cereals. | | Definition | ChEBI: A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A fungicide used to control Erysiphe, Helminthosporium and
ital>Rhynchospium in cereals. | | Metabolic pathway | Limited information is available to describe the degradation and metabolic
fate of pyrazophos. Hydrolytic cleavage of the P-O-pyrazolopyrimidine
linkage is the primary metabolic pathway. Oxidative
desulfuration of pyrazophos to pyrazophos-oxon is only a minor
pathway, observed in the plant metabolism study (Scheme 1). | | Metabolism | Its mode of action is believed to be the inhibition of
melanin biosynthesis and the development of appressoria
by fungal conidia. Formulation is available as emulsifiable
concentrate (EC: 30%). Application rates on Oidium spp.
are in the range of 15–30 g a.i./hl. | | Degradation | Pyrazophos (1) is hydrolysed in acidic or alkaline solution (PM). |
| | PYRAZOPHOS Preparation Products And Raw materials |
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