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(-)-alpha-Copaene manufacturers
- (-)-ALPHA-COPAENE
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- $1.00
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2024-08-13
- CAS:3856-25-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
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| | (-)-alpha-Copaene Basic information |
| Product Name: | (-)-alpha-Copaene | | Synonyms: | Aglaiene;Copaen;Tricyclo[4.4.0.0(2,7)]dec-3-ene, 1,3-dimethyl-8-(1-methylethyl)-, st;Tricyclo[4.4.0.0(2,7)]dec-3-ene, 8-isopropyl-1,3-dimethyl-;Tricyclo[4.4.0.02,7]dec-3-ene, 1,3-dimethyl-8-(1-methylethyl)-, stereoisomer;Tricyclo[4.4.0.02,7]dec-3-ene, 8-isopropyl-1,3-dimethyl-, (1R,2S,6S,7S,8S)-(-)-;8-isopropyl-1,3-dimethyltricyclo[4.4.0.02,7]dec-3-ene;C15 H24, Copaen [Tricyclo(4.4.0.02.7)dec-3-ene, 1,3-dimethyl-8-(1-methylethyl)-] | | CAS: | 3856-25-5 | | MF: | C15H24 | | MW: | 204.35 | | EINECS: | 223-364-4 | | Product Categories: | | | Mol File: | 3856-25-5.mol |  |
| | (-)-alpha-Copaene Chemical Properties |
| Melting point | 74 °C | | Boiling point | 124 °C15 mm Hg(lit.) | | alpha | D22 -6.3° (c = 1.20 in chloroform) | | density | 0.910 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.490 | | storage temp. | −20°C | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | form | Oil | | color | Colourless | | Odor | at 100.00 %. woody spicy honey | | Odor Type | woody | | LogP | 5.710 |
| | (-)-alpha-Copaene Usage And Synthesis |
| Description | α-Copaene is a sesquiterpene found in a variety of plants, including Cannabis, that has antiproliferative and antioxidant properties. It inhibits proliferation of primary rat neurons and N2a rat neuroblastoma cells in a concentration-dependent manner and cultured human lymphocytes when used at concentrations greater than 100 mg/L. α-Copaene (25 mg/L) increases total antioxidant capacity in primary rat neurons and N2a neuroblastoma cells, as well as cultured human lymphocytes, when used at concentrations of 50 and 100 mg/L. | | Uses | α-Copaene is a tricyclicsesquiterpenesand can be extracted from the oil of S. aethiopis. It also exhibit anti-plasmodial activity againstP. falciparum in culture. | | Definition | ChEBI: A sesquiterpene that is tricyclo[4.4.0.02,7]dec-3-ene bearing an isopropyl substituent at position 8 and two methyl substituents at positions 1 and 3 (the 1S,6S,7S,8S-
iastereomer). | | Purification Methods | Purify it by distillation, preferably under vacuum. [Heathcock J Am Chem Soc 88 4110 1966, Heathcock et al. J Am Chem Soc 89 4133 1967, Corey & Watt J Am Chem Soc 95 2303 1973, Beilstein 5 IV 1189.] | | References | [1] MARIE MARCHINI . Multidimensional analysis of cannabis volatile constituents: Identification of 5,5-dimethyl-1-vinylbicyclo[2.1.1]hexane as a volatile marker of hashish, the resin of Cannabis sativa L.[J]. Journal of Chromatography A, 2014, 1370: Pages 200-215. DOI: 10.1016/j.chroma.2014.10.045
[2] HASAN TüRKEZ Baak T Kübra Celik. Effects of copaene, a tricyclic sesquiterpene, on human lymphocytes cells in vitro.[J]. Cytotechnology, 2014, 66 4: 597-603. DOI: 10.1007/s10616-013-9611-1
[3] H. TURKEZ. Cytotoxic and cytogenetic effects of α-copaene on rat neuron and N2a neuroblastoma cell lines[J]. Biologia, 2014, 9 1: 936-942. DOI: 10.2478/s11756-014-0393-5 |
| | (-)-alpha-Copaene Preparation Products And Raw materials |
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