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5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID manufacturers
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| | 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID Basic information | | Synthesis Uses |
| | 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID Chemical Properties |
| Melting point | 160-164 °C(lit.) | | Boiling point | 434.7±33.0 °C(Predicted) | | density | 1.320 | | storage temp. | 2-8°C | | solubility | soluble in Methanol | | pka | 3.33±0.10(Predicted) | | form | Crystalline | | color | White | | InChI | InChI=1S/C10H7NO3/c12-10(13)8-6-9(14-11-8)7-4-2-1-3-5-7/h1-6H,(H,12,13) | | InChIKey | XJYOBHXWBRKOQO-UHFFFAOYSA-N | | SMILES | O1C(C2=CC=CC=C2)=CC(C(O)=O)=N1 | | CAS DataBase Reference | 14441-90-8(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38-42/43 | | Safety Statements | 26-36-45 | | WGK Germany | 2 | | HazardClass | IRRITANT | | HS Code | 2934999090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 |
| | 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID Usage And Synthesis |
| Synthesis | The target compound 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID was prepared by hydrolysis using 5-phenyl-3-isoxazole carboxylic acid ester as the starting material [1]. The synthetic reaction formula is shown in the figure below: 
| | Uses | 5-Phenylacetic acid is a carboxylic acid derivative that can be used as an intermediate in organic synthesis. | | Description | 5-Phenylisoxazole-3-carboxylic acid is a phenoxy compound, can be used in pharmaceutical research. | | Biological Activity | 5-phenylisoxazole-3-carboxylic acid and derivatives have the ability to inhibit xanthine oxidase (XO). XO is a key enzyme in the last two steps of purine metabolic pathway, catalyzing the oxidation of hypoxanthine to xanthine, and then to urid acid, which associated with gout and hyperuricemia. | | Safety | 5-Phenylisoxazole-3-carboxylic acid is a compound that is irritating to humans. It is acutely toxic if ingested. Skin contact causes skin irritation and may also trigger allergic skin reactions. Accidental contact with the eyes may cause severe eye irritation. Inhalation may cause allergic reactions, asthma symptoms or breathing difficulties. |
| | 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials |
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