(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE
| 中文名称 | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE |
|---|---|
| 中文同义词 | 化合物 T23218;(R)-(+)-8-羟基-DPAT氢溴酸盐(8-羟基 DPAT);(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE (8-HYDROXY DPAT),5-HT1A RECEPTOR激动剂;(R)-7-(二丙氨基)-5,6,7,8-四氢萘-1-醇盐酸盐;(R)-(+)- 8-羟基-DPAT氢溴酸盐 |
| 英文名称 | (R)-(+)-8-Hydroxy-dpat hydrobromide |
| 英文同义词 | R(+)-8-HYDROXY-DPAT HYDROBROMIDE FULL 5- HT1A SEROTONIN;(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;Hydroxy-DPAT hydrobromide, (R)-(+)-8-;(R) (+) 8 Hydroxy DPAT hydrobromide,(R)(+)8HydroxyDPAT hydrobromide;(R)-(+)-8-Hydroxy-DPAT hydrobromide (8-Hydroxy DPAT), 5-HT1A receptor agonist;R(+)-8-OH-DPAT hydrobromide;(R)-(+)-8-Hydroxy-DPAT hydrobromide |
| CAS号 | 78095-19-9 |
| 分子式 | C16H25NO.BrH |
| 分子量 | 328.291 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 78095-19-9.mol |
| 结构式 |  |
(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE 性质
| 储存条件 | protect from light |
|---|---|
| 溶解度 | ±60°C在水中的溶解度>10mg/mL（超声处理） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 旋光度 (Optical Rotation) | [α]25/D +68.2°, c = 1 in methanol(lit.) |
| 水溶解性 | H2O: >10mg/mL at±60°C (with sonication) |
| InChI | 1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1 |
| InChIKey | BATPBOZTBNNDLN-PFEQFJNWSA-N |
| SMILES | Br.CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 |
R(+)-8-OH-DPAT ((R)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide 是一种有效的 5-HT1A 激动剂。R(+)-8-OH-DPAT hydrobromide 可增强 SUL (HY-B1059) 诱导的内侧前额叶皮质 (mPFC) 中的多巴胺 (DA) 释放。