N-PALMITOYL-D-SPHINGOMYELIN manufacturers
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| | N-PALMITOYL-D-SPHINGOMYELIN Basic information |
| Product Name: | N-PALMITOYL-D-SPHINGOMYELIN | | Synonyms: | P-SPM;n-palmitoyl-d-sphingomyelin semisynthetic from bovine brain sphingomyelin;N-palMitoyl-D-erythro-sphingosylphosphorylcholine;(2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-3-hydroxy-1-phosphocholine;16:0 SM (d18:1/16:0);C16 Sphingomyelin;N-(Hexadecanoyl)-sphing-4-enine-1-phosphocholine;N-PALMITOYL-D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE;16:0 SM (D18:1/16:0) | | CAS: | 6254-89-3 | | MF: | C39H79N2O6P | | MW: | 703.028121 | | EINECS: | | | Product Categories: | | | Mol File: | 6254-89-3.mol |  |
| | N-PALMITOYL-D-SPHINGOMYELIN Chemical Properties |
| storage temp. | −20°C | | solubility | Ethanol: 10 mg/ml | | form | powder or crystals | | color | White to off-white | | BRN | 4833682 | | InChIKey | RWKUXQNLWDTSLO-UWSOPVLFNA-N | | SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N([H])C(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C |&1:15,17,r| |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | N-PALMITOYL-D-SPHINGOMYELIN Usage And Synthesis |
| Uses | N-palmitoyl-D-erythro-sphingosylphosphorylcholine (16:0 SM (d18:1/16:0)) has been used as a standard for the quantitation of sphingolipid metabolites. It has also been used for the quantification of lipids in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS). It may be used in liposomes to measure ostreolysin A (OlyA) binding to determine the effects of phosphatidylcholines (PCs) on sphingomyelin (SM)/cholesterol interactions. | | Definition | ChEBI: A sphingomyelin 34:1 in which the N-acyl group and sphingoid base are specified as hexadecanoyl and sphingosine respectively. | | in vivo | N-Palmitoyl-D-Sphingomyelin (100 μM, 3 days) combined with a respiratory chain inhibitor rescues cell death induction in HCT116 spheroids[2].
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| | N-PALMITOYL-D-SPHINGOMYELIN Preparation Products And Raw materials |
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