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| | L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Basic information |
| Product Name: | L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL | | Synonyms: | L-A-lysophosphatidylcholine,*stearoyl (C18:0);1-Stearoyl-L-alpha-lysolecithine;l-α-lysophosphatidylcholine, stearoyl;L-α-Lysophosphatidylcholine, stearoyl, Lysolecithin, stearoyl;1-Stearoyl-2-hydroxy-sn-glycero-3-phosphocholine L-1518;Stearoyl L-α-Lysolecithin;1-Stearoyl-2-lyso-sn-glycero-3-PC;1-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLI | | CAS: | 19420-57-6 | | MF: | C26H54NO7P | | MW: | 523.68 | | EINECS: | | | Product Categories: | | | Mol File: | 19420-57-6.mol |  |
| | L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Chemical Properties |
| Melting point | 100-200 °C | | density | 1,00 g/ml | | storage temp. | -20°C | | solubility | Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated) | | form | powder | | color | white | | biological source | synthetic (organic) | | Stability: | Hygroscopic, Moisture Sensitive | | InChI | InChI=1/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3/t25-/s3 | | InChIKey | IHNKQIMGVNPMTC-RUZDIDTESA-N | | SMILES | C(OP([O-])(=O)OCC[N+](C)(C)C)[C@H](O)COC(=O)CCCCCCCCCCCCCCCCC |&1:12,r| |
| WGK Germany | 3 | | HS Code | 2923.90.0100 | | Storage Class | 11 - Combustible Solids |
| | L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Usage And Synthesis |
| Description | Lyso-PC (18:0), also known as 1-stearoyl-sn-glycero-3-phosphocholine, is a lysophosphocoline connceted to hydrophobic fatty acid tail (stearic acid) by a glycerol. | | Uses | Stearoyl L-α-Lysolecithin is an bioactive lysophosphatidylcholine derived compound found to be released by bronchial epithelial cells. Stearoyl L-α-Lysolecithin have also been utilized in the development of liposomes and michelles by drug transdermal delivery devices. | | Uses | 18:0 Lyso PC has been used:
- to functionalize carbon nanotubes (CNTs) for the development of methods to attach DNA to CNTs
- to increase the level of lysophosphatidic acid (LPA) in mouse
- to induce TNF receptor associated factor 3 interacting protein 2 (TRAF3IP2) expression in endothelial cells (EC)
| | Definition | ChEBI: 1-stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 18:0 in which the acyl substituent is located at position 1 and is specified as stearoyl. It has a role as a mouse metabolite and an apoptosis inducer. It is a 1-O-acyl-sn-glycero-3-phosphocholine and a lysophosphatidylcholine 18:0. It is functionally related to an octadecanoic acid. | | Biochem/physiol Actions | 1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles. | | IC 50 | HDAC3; p-STAT3 |
| | L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Preparation Products And Raw materials |
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