| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:VH 032 amide-alkylC8-amine
CAS:2341796-80-1
Purity:>98% Package:1mg;10mg;50mg;100mg;
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VH 032-linker 11 manufacturers
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| | VH 032-linker 11 Basic information |
| Product Name: | VH 032-linker 11 | | Synonyms: | VH 032-linker 11;VH 032 amide-alkylC8-amine;VH 032 amide-alkylC8-amine dihydrochloride;(S,R,S)-AHPC-C8-NH2 dihydrochloride;(2S,4R)-1-[(S)-2-(9-Aminononanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[4-(4-methylthiazol-5-yl)benzyl]pyrrolidine-2-carboxamide Dihydrochloride | | CAS: | 2341796-80-1 | | MF: | C31H48ClN5O4S | | MW: | 622.27 | | EINECS: | | | Product Categories: | | | Mol File: | 2341796-80-1.mol |  |
| | VH 032-linker 11 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | VH 032-linker 11 Usage And Synthesis |
| Uses | (S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesizedE3 ligase ligand-linker conjugatethat incorporates the VH032 based VHL ligand and a linker used forAKTPROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1]. | | IC 50 | VHL | | storage | Store at -20°C | | References | [1] [1].Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1. |
| | VH 032-linker 11 Preparation Products And Raw materials |
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