|
|
| | 2-Amino-cyclohex-1-enecarboxylic acid ethyl ester Basic information |
| Product Name: | 2-Amino-cyclohex-1-enecarboxylic acid ethyl ester | | Synonyms: | ETHYL-(2-AMINOCYCLOHEX-1-EN-1-CARBOXYLAT);ETHYL 2-AMINOCYCLOHEX-1-ENE-1-CARBOXYLATE;ETHYL 2-AMINO-1-CYCLOHEXENE-1-CARBOXYLATE;Ethyl 2-amino-1-cyclohexene-1-carboxylate,98%;2-Amino-1-cyclohexenecarboxylic acid ethyl ester;1-Cyclohexene-1-carboxylicacid, 2-aMino-, ethyl ester;Ethyl 2-aMinocyclohex-1-enecarboxylate;2-aminocyclohexene-1-carboxylic acid ethyl ester | | CAS: | 1128-00-3 | | MF: | C9H15NO2 | | MW: | 169.22 | | EINECS: | | | Product Categories: | | | Mol File: | 1128-00-3.mol |  |
| | 2-Amino-cyclohex-1-enecarboxylic acid ethyl ester Chemical Properties |
| Melting point | 70-74 °C | | Boiling point | 298.52°C (rough estimate) | | density | 1.0873 (rough estimate) | | refractive index | 1.4580 (estimate) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | Crystals or Crystalline Powder | | pka | 6.97±0.20(Predicted) | | color | White to light yellow |
| Safety Statements | 24/25 | | HS Code | 29224999 |
| Provider | Language |
|
ACROS
| English |
| | 2-Amino-cyclohex-1-enecarboxylic acid ethyl ester Usage And Synthesis |
| Chemical Properties | white to light yellow crystals or | | Definition | ChEBI: Ethyl-2-amino-1-cyclohexene-1-carboxylate is an enamine and an enone. | | Synthesis | a) To a solution of ethyl 2-cyclohexanone carboxylate (18.9 mL, 118 mmol) in methanol (120 mL) was added ammonium carbamate (9.20 g, 118 mmol). The reaction mixture was stirred at room temperature for 1 hour until the ammonium carbamate was completely dissolved. After continuing to stir the reaction mixture for 1 h, the volatile solvent was removed by distillation under reduced pressure to afford ethyl 2-amino-1-cyclohexene-1-carboxylate as a white to pale yellow solid (19.9 g, quantitative yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.28 (t, J = 7.2 Hz, 3H), 1.57-1.71 (m, 4H), 2.21 (t, J = 6.1 Hz, 2H), 2.26 (t, J = 6.1 Hz, 2H), 4.15 (q, J = 7.2 Hz, 2H), 6.06 (br s, 2H) . | | References | [1] Patent: WO2013/26900, 2013, A1. Location in patent: Page/Page column 60
[2] New Journal of Chemistry, 2005, vol. 29, # 6, p. 769 - 772
[3] Tetrahedron Letters, 2013, vol. 54, # 9, p. 1133 - 1136
[4] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 14, p. 3654 - 3669
[5] Chemistry of Heterocyclic Compounds, 2006, vol. 42, # 6, p. 765 - 775 |
| | 2-Amino-cyclohex-1-enecarboxylic acid ethyl ester Preparation Products And Raw materials |
|