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Methyl 3-hydroxybenzoate

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CAS:19438-10-9
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Methyl 3-hydroxybenzoate manufacturers

  • Methyl 3-hydroxybenzoate
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  • 2026-02-27
  • CAS:19438-10-9
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  • Methyl 3-hydroxybenzoate
  • Methyl 3-hydroxybenzoate pictures
  • $100.00 / 1kg
  • 2024-04-27
  • CAS:19438-10-9
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Methyl 3-hydroxybenzoate Basic information
Uses
Product Name:Methyl 3-hydroxybenzoate
Synonyms:METHYL M-HYDROXYBENZOATE;3-HYDROXYBENZOIC ACID METHYL ESTER;AKOS BBB/380;AKOS BBS-00004297;M-HYDROXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0067;Benzoic acid, 3-hydroxy-, methyl ester;METHYL 3-HYDROXYBENZOATE
CAS:19438-10-9
MF:C8H8O3
MW:152.15
EINECS:243-071-5
Product Categories:FINE Chemical & INTERMEDIATES;Aromatic Esters;Aromatics Compounds;Aromatics;C8 to C9;Carbonyl Compounds;Esters;bc0001
Mol File:19438-10-9.mol
Methyl 3-hydroxybenzoate Structure
Methyl 3-hydroxybenzoate Chemical Properties
Melting point 70-72 °C (lit.)
Boiling point 280-281 °C/709 mmHg (lit.)
density 1.1528
refractive index 1.4447 (estimate)
Fp 280-281°C/708mm
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in chloroform, dimetyl Sulfoxide,ethanol and methanol.
pka9.15±0.10(Predicted)
form Crystals
color Beige
BRN 2208129
InChIInChI=1S/C8H8O3/c1-11-8(10)6-3-2-4-7(9)5-6/h2-5,9H,1H3
InChIKeyYKUCHDXIBAQWSF-UHFFFAOYSA-N
SMILESC(OC)(=O)C1=CC=CC(O)=C1
LogP1.890
CAS DataBase Reference19438-10-9(CAS DataBase Reference)
NIST Chemistry Reference3-HO-C6H4-COOCH3(19438-10-9)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29163100
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Methyl 3-hydroxybenzoate Usage And Synthesis
UsesMethyl 3-Hydroxybenzoate can be used to increase the stability of agents to treat keratin material.
Chemical PropertiesWhite Solid
UsesMethyl 3-hydroxybenzoate is used in the preparation of 3-hydroxybenzene-1,2-dicarbaldehyde and O-methyl O-[3-methyl-4-(methylthio)phenyl]O-(3-methylcarboxyphenyl) phosphorothioate.
UsesMethyl 3-hydroxybenzoate has been used in synthesis of:
  • 3-hydroxybenzene-1,2-dicarbaldehyde
  • O-methyl O-[3-methyl-4-(methylthio)phenyl]O-(3-methylcarboxyphenyl) phosphorothioate
DefinitionChEBI: Methyl 3-hydroxybenzoate is a benzoate ester resulting from the formal condensation of the carboxy group of 3-hydroxybenzoic acid with methanol. It has a role as an antibacterial agent. It is a benzoate ester, a member of phenols and a methyl ester. It is functionally related to a 3-hydroxybenzoic acid.
Synthesis Reference(s)Synthetic Communications, 16, p. 331, 1986 DOI: 10.1080/00397918608076314
Synthesis

In the three-port bottle add 3-hydroxybenzoic acid, methanol and hydroxybenzenesulfonic acid, 3-hydroxybenzoic acid and methanol molar ratio of 1:4, the amount of hydroxybenzenesulfonic acid added to the total mass of the reactants of 8.6%, the three-port bottle left mouth plug wear mouth plugs, the right side of the mouth mounted probe tube (inside the temperature probe), the middle mouth of the air condensate tube through the top of the furnace mouth connected to the outside, respectively, mounted on the water separator, water condensate tube, mixing evenly, and then into the electromagnetic stirrer, placed in the microwave oven, start stirring, stirring speed of 300r/min, start the reaction, the reaction process in a timely manner to release the water distributor within the water, in which the microwave oven microwave radiation power of 150W, the microwave radiation temperature of 85 C, the microwave radiation time of 40min; mixed evenly, and then into the electromagnetic stirrer, placed in the microwave oven, start stirring, and then into the microwave oven, the microwave oven, the microwave oven, the reaction process in a timely manner, the microwave oven, the microwave oven, the microwave oven. Start the reaction, the reaction process in time to release the water separator water;

Reaction 1h after the closure of the power supply, the reaction of the liquid into a clean three-mouth bottle and steam distillation of excess methanol, distillation residue is dumped into a clean beaker, cooled precipitation, washed with 10% sodium carbonate solution to pH 7.0-8.0, pumping, rinsing the filter cake with distilled water, drying, refining to obtain white The solid product is methyl 3-hydroxybenzoate. The yield of methyl 3-hydroxybenzoate was determined to be 84.1%.

Methyl 3-hydroxybenzoate Preparation Products And Raw materials
Raw materialsMethylparaben
Preparation Products3-Hydroxybenzoic acid-->3-Cyanophenol-->METHYL 4-FORMYL-3-HYDROXYBENZOATE-->Methyl 3-methoxybenzoate-->3-BENZYLOXYBENZYL ALCOHOL-->3-ETHOXYBENZOIC ACID-->(-)-FENCHONE
Tag:Methyl 3-hydroxybenzoate(19438-10-9) Related Product Information
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