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3,5-Dichloroanisole

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3,5-Dichloroanisole manufacturers

  • 3,5-Dichloroanisole
  • 3,5-Dichloroanisole pictures
  • 2026-06-30
  • CAS:33719-74-3
  • Min. Order: 1KG
  • Purity: 98.0%
  • Supply Ability: 10000KGS
3,5-Dichloroanisole Basic information
Product Name:3,5-Dichloroanisole
Synonyms:3,5-DICHLOROANISOLE;3,5-DICHLORANISOL;Benzene, 1,3-dichloro-5-methoxy-;TOLCLOFOS-METHYL PESTANAL, 250 MG;3,5-Dichloroanisole 98%;3.5-Dichloroan;3,5-Dichloroanisole,98%;3,5-Dichloroanisole,1,3-Dichloro-5-methoxybenzene
CAS:33719-74-3
MF:C7H6Cl2O
MW:177.03
EINECS:251-655-6
Product Categories:Aromatic Ethers;Anisole;Anisoles, Alkyloxy Compounds & Phenylacetates;Chlorine Compounds
Mol File:33719-74-3.mol
3,5-Dichloroanisole Structure
3,5-Dichloroanisole Chemical Properties
Melting point 39-41 °C (dec.) (lit.)
Boiling point 97°C 7,6mm
density 1.289±0.06 g/cm3(Predicted)
Fp 223 °F
storage temp. Refrigerator
solubility Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
BRN 1936395
Henry's Law Constant2.3×10-3 mol/(m3Pa) at 25℃, Pfeifer et al. (2001)
InChI1S/C7H6Cl2O/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3
InChIKeySSNXYMVLSOMJLU-UHFFFAOYSA-N
SMILESCOc1cc(Cl)cc(Cl)c1
CAS DataBase Reference33719-74-3(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 3,5-dichloro-1-methoxy-(33719-74-3)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-20/22
Safety Statements 22-24/25-37/39-26
WGK Germany 3
HS Code 29093090
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
3,5-Dichloroanisole Usage And Synthesis
Chemical PropertiesWhite to yellow crystalline powder
Uses3,5-Dichloroanisole, is a chlorinated anisole derivative, possessing possible antibacterial activity. It is also an organic building block that can be used for the synthesis of chlorinated chemical compounds, such as polychlorinated dibenzofurans (PCDD/F).
General Description3,5-Dichloroanisole on nitration under mild conditions yields 3,5-dichloro-2,4,6-trinitroanisole. The 35Cl Nuclear Quadrupole Resonance (NQR) frequency and spin lattice relaxation time in 3,5-dichloroanisole has been measured.
SynthesisUnder the protection of nitrogen, 2L reaction flask was added 1,3,5-trichlorobenzene 254.1 g (1.4 mol), sodium methanol 151.2 g (2.8 mol, 30% methanol solution), heating to 65 ~ 75 , holding, tracking the reaction detection until the reaction is complete, filtration, 400 g of dichloromethane extraction, washed with water to neutral, drying, stripping off the solvent to get 3,5-dichloroanisole Crude product, plus spiked fractionation column for distillation, to get the main fraction 229.1 g, yield 93%, GC: 92%.
References[1] Emsley, J., et al. “Conformations of 3,5-Dichloroanisole and 3,5-Dibromoacetophenone Determined from 1H Nuclear Magnetic Resonance Spectra of Nematic Solutions.” Journal of The Chemical Society-Perkin Transactions 1, 1995 1, 1976, pp. 805–07, https://doi.org/10.1039/P29760000805.
3,5-Dichloroanisole Preparation Products And Raw materials
Raw materials1,3,5-Trichlorobenzene-->Sodium Methoxide-->Dichloromethane
Preparation Products3,5-Dichlorophenol
Tag:3,5-Dichloroanisole(33719-74-3) Related Product Information
3,5-Dichlorobenzoic acid Guaiacol Dichloroethane Anisole 3,5-Dimethylanisole 3,5-Difluoroanisole Thionyl chloride 2-Chloroanisole 4-Methoxyphenol 1,3-Dichloropropene 2,5-Dichlorobenzoic acid 2,3,5,6-TETRACHLOROANISOLE 2,3,4,5-TETRACHLOROANISOLE L-PYROGLUTAMIC ACID PENTACHLOROPHENYL ESTER PENTACHLOROPHENOL DODECANOATE 2,3-DICHLOROANISOLE PESTANAL 2-(3,5-Dichlorophenoxy)ethanethioamide 2-(3,5-Dichlorophenoxy)acetonitrile