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| | 4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile Basic information |
| Product Name: | 4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile | | Synonyms: | 4-Amino-2-(ethylthio)-5-pyrimidinecarbonitrile;5-Cyano-4-amino-2-ethylsulfanylpyrimidine;5-PyriMidinecarbonitrile,4-aMino-2-(ethylthio)-;4-amino-2-(ethylthio)pyrimidine-5-carbonitrile;4-Amino-2-ethylsulfanyl-pyrimidine;4-AMINO-2-ETHYLSULFANYL-PYRIMIDINE-5-CARBONITRILE ISO 9001：2015 REACH;4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile | | CAS: | 16462-29-6 | | MF: | C7H8N4S | | MW: | 180.23 | | EINECS: | | | Product Categories: | | | Mol File: | 16462-29-6.mol |  |
| | 4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | Appearance | Off-white to light yellow Solid |
| | 4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile Usage And Synthesis |
| Synthesis | 2-Ethyl-2-thiourea hydrobromide (1.52 g, 8.19 mmol) and (ethoxymethylene)malononitrile (1.0 g, 8.19 mmol) were added to a solution of N,N-diisopropylethylamine (3.57 mL, 20.05 mmol) in ethanol (20 mL). The reaction mixture was stirred at room temperature for 3.5 hours. Upon completion of the reaction, the resulting solid product was collected by filtration and washed with ethanol. Finally, the product was dried under vacuum to afford 4-amino-2-(ethylthio)-5-pyrimidine as a light yellow solid (580 mg, 39% yield). | | References | [1] Patent: WO2008/133753, 2008, A2. Location in patent: Page/Page column 115
[2] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 6, p. 2212 - 2215 |
| | 4-Amino-2-ethylsulfanyl-pyrimidine-5-carbonitrile Preparation Products And Raw materials |
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