- 7-Bromo-4-chromanone
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- $124.00 / 5g
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2025-09-16
- CAS:18442-22-3
- Min. Order: 5g
- Purity: 0.98
- Supply Ability: 25kg
- 7-Bromo-4-chromanone
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- $0.00 / 1KG
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2022-01-04
- CAS:18442-22-3
- Min. Order: 1g
- Purity: 98%minHPLC
- Supply Ability: 200kgs/month
- 7-Bromo-4-chromanone
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- $1.00 / 1g
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2020-01-15
- CAS:18442-22-3
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 1000KGS
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| | 7-bromochroman-4-one Basic information |
| Product Name: | 7-bromochroman-4-one | | Synonyms: | 7-Bromo-4-chromanone;7-Bromo Chromonone;7-bromo-2,3-dihydrochromen-4-one;7-Bromo-2,3-dihydro-4H-1-benzopyran-4-one;7-broMo-3,4-dihydro-2H-1-benzopyran-4-one;7-BroMo-4-chroManone 97%;7-Bromochroman-4-one C9H7BrO2;7-bromo-2,3-dihydrobenzopyran-4-one | | CAS: | 18442-22-3 | | MF: | C9H7BrO2 | | MW: | 227.05 | | EINECS: | 1308068-626-2 | | Product Categories: | 18442-22-3 | | Mol File: | 18442-22-3.mol |  |
| | 7-bromochroman-4-one Chemical Properties |
| Boiling point | 336.6±42.0 °C(Predicted) | | density | 1.621±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | Appearance | White to yellow Solid | | InChI | InChI=1S/C9H7BrO2/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-2,5H,3-4H2 | | InChIKey | DMEAYYYHWLCPCD-UHFFFAOYSA-N | | SMILES | C1OC2=CC(Br)=CC=C2C(=O)C1 |
| | 7-bromochroman-4-one Usage And Synthesis |
| Uses | Used as a intermediate for R & D. | | Synthesis | 7-Bromochroman-4-one was synthesized by hydrogenation addition of 7-Bromo-benzopyrone catalyzed by Wilkinson's catalyst Rhodium( Ⅰ) tris( triphenylphosphine) chloride[Rh( PPh3)3Cl]. The structure was confirmed by1 H NMR and MS. The optimum reaction conditions for synthesizing 7-Bromochroman-4-one were as follows: 5 0. 329 mol,ethanol as the solvent,c( 5) =0. 4 mol·L- 1,4% mol Rh( PPh3)3Cl as the catalyst,under 0. 3 MPa of hydrogen pressure,at 70℃ for 20 h,the yield was 79. 8%. | | References | [1] Patent: WO2012/68234, 2012, A2. Location in patent: Page/Page column 629; 630
[2] Patent: WO2007/88450, 2007, A2. Location in patent: Page/Page column 22
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 22, p. 10228 - 10243
[4] Patent: US2014/200215, 2014, A1. Location in patent: Paragraph 1148; 1150
[5] Patent: US2009/202478, 2009, A1 |
| | 7-bromochroman-4-one Preparation Products And Raw materials |
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