- 8-Bromochroman-4-one
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- $89.00 / 5g
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2026-05-25
- CAS:204377-88-8
- Min. Order: 5g
- Purity: 0.99
- Supply Ability: 25kg
- 8-Bromo-4-chromanone
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- $0.00 / 1KG
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2022-01-04
- CAS:204377-88-8
- Min. Order: 1g
- Purity: 98%minHPLC
- Supply Ability: 50kgs/month
- 8-Bromo-4-chromanone
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- $1.00 / 1KG
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2020-01-03
- CAS:204377-88-8
- Min. Order: 1KG
- Purity: 95-99%
- Supply Ability: 1ton
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| | 8-Bromo-4-chromanone Basic information | | Uses |
| Product Name: | 8-Bromo-4-chromanone | | Synonyms: | 8-Bromo-4-chromanone;8-Bromo-2,3-dihydro-4H-1-benzopyran-4-one;8-broMo-3,4-dihydro-2H-1-benzopyran-4-one;8-BroMo-4-chroManone 97%;8-bromo-chroman-4-one;8-broMo-2,3-dihydrochroMen-4-one;8-bromo-2,3-dihydro-4H-chromen-4-one;8-BROMO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE | | CAS: | 204377-88-8 | | MF: | C9H7BrO2 | | MW: | 227.05 | | EINECS: | 1312995-182-4 | | Product Categories: | | | Mol File: | 204377-88-8.mol |  |
| | 8-Bromo-4-chromanone Chemical Properties |
| Boiling point | 339℃ | | density | 1.621 | | Fp | 159℃ | | storage temp. | Sealed in dry,Room Temperature | | Appearance | White to light yellow Solid |
| | 8-Bromo-4-chromanone Usage And Synthesis |
| Uses | 8-Bromo-4-dihydrochromone is an important intermediate, but its synthesis yield is low, it is difficult to synthesize, and its selling price is more than 20 times that of the similar product 6-bromo-3-dihydrochromone. | | Synthesis | Step 3: Synthesis of 8-bromo-benzotetrahydropyran-4-one (P34c)
Compound P34b (2.0 g, 8.15 mmol) was dissolved in ethylene glycol (20 mL) and heated to reflux for 4 hours. After completion of the reaction, the reaction mixture was cooled, poured into water and extracted twice with ether (Et2O). The organic layers were combined and washed sequentially with 1 M aqueous sodium hydroxide (NaOH) and saturated aqueous ammonium bicarbonate (NH4HCO3). The organic layers were dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated, and finally purified by column chromatography (eluent: petroleum ether/ethyl acetate = 50/1) to afford the target compound P34c (0.88 g, 48% yield) as a yellow solid. | | References | [1] Patent: WO2012/139775, 2012, A1. Location in patent: Page/Page column 60-61 |
| | 8-Bromo-4-chromanone Preparation Products And Raw materials |
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