MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan

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Company Name: Nantong QuanYi Biotechnology Co., Ltd  
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Company Name: TargetMol Chemicals Inc.  
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MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan manufacturers
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Basic information
Product Name:MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
Synonyms:MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
CAS:2414393-22-7
MF:C55H60FN9O13
MW:1074.12
EINECS:
Product Categories:
Mol File:2414393-22-7.mol
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Structure
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Chemical Properties
density 1.48±0.1 g/cm3(Predicted)
pka11.18±0.40(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Usage And Synthesis
UsesMC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer[1].
IC 50Camptothecins
References[1] HUA Haiqing, et al. Antibody-drug conjugate and medical use thereof. Patent WO2021190564A1.
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Preparation Products And Raw materials
Tag:MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan(2414393-22-7) Related Product Information
ZBH-1205 Exatecan mesylate dihydrate Glycinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 11-(aminomethyl)-4-ethyl-8-fluoro-4-hydroxy-9-methyl-, (4S)- Glycine, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ester, hydrochloride (1:1) DIBAC-GGFG-NH2CH2-Dxd