2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)-

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2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- manufacturers

  • hCAIX-IN-5
  • hCAIX-IN-5 pictures
  • $163.00
  • 2026-07-27
  • CAS:2451479-57-3
  • Purity: 99.26%
  • Supply Ability: 10g
2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Basic information
Product Name:2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)-
Synonyms:2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)-;hCAIX-IN-5
CAS:2451479-57-3
MF:C18H12FNO3
MW:309.29
EINECS:
Product Categories:
Mol File:2451479-57-3.mol
2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Structure
2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Chemical Properties
Boiling point 565.9±50.0 °C(Predicted)
density 1.385±0.06 g/cm3(Predicted)
pka11.80±0.20(Predicted)
Safety Information
MSDS Information
2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Usage And Synthesis
UseshCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].
References[1] Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586. DOI:10.1016/j.bmc.2020.115586
2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Preparation Products And Raw materials
Tag:2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)-(2451479-57-3) Related Product Information
4-Fluoro-N-(2-oxo-2H-1-benzopyran-6-yl)benzamide 6-ACETAMIDOCOUMARIN 2-Propenamide, 3-(4-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- AURORA 3455 2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- 2H-1-Benzopyran-3-carboxamide, N-(4-fluorophenyl)-6-methoxy-