2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- manufacturers
- hCAIX-IN-7
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- $2500.00
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2026-07-27
- CAS:2451479-58-4
- Purity:
- Supply Ability: 10g
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| | 2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Basic information |
| | 2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Chemical Properties |
| Boiling point | 565.9±50.0 °C(Predicted) | | density | 1.385±0.06 g/cm3(Predicted) | | pka | 11.67±0.20(Predicted) |
| | 2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Usage And Synthesis |
| Uses | hCAIX-IN-7 (compound 6c) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1]. | | References | [1] Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586. DOI:10.1016/j.bmc.2020.115586 |
| | 2-Propenamide, 3-(3-fluorophenyl)-N-(2-oxo-2H-1-benzopyran-6-yl)-, (2E)- Preparation Products And Raw materials |
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