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| | 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid Basic information |
| Product Name: | 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid | | Synonyms: | 2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid;2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid;3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid;α,3,4-Trihydroxybenzenepropanoic acid;α,3,4-Trihydroxybenzenepropionic acid;α-Hydroxyhydrocaffeic acid;alpha,3,4-Trihydroxy-benzenepropanoic acid;3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid | | CAS: | 23028-17-3 | | MF: | C9H10O5 | | MW: | 198.17 | | EINECS: | | | Product Categories: | | | Mol File: | 23028-17-3.mol |  |
| | 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid Chemical Properties |
| Boiling point | 481.5±40.0 °C(Predicted) | | density | 1.546±0.06 g/cm3 (20 ºC 760 Torr) | | pka | 3.82±0.10(Predicted) | | form | Solid | | color | Light yellow to yellow | | LogP | 0.045 (est) |
| | 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid Usage And Synthesis |
| Uses | (Rac)-Salvianic acid A is the racemate of Salvianic acid A (HY-N1913). Salvianic acid A, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research[1][2][3]. | | Definition | ChEBI: 3-(3,4-dihydroxyphenyl)lactic acid is a 2-hydroxy monocarboxylic acid and a member of catechols. It is functionally related to a rac-lactic acid. It is a conjugate acid of a 3-(3,4-dihydroxyphenyl)lactate. | | References | [1] Wei Wang, et al. Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation. Acta Pharmacol Sin. 2022 Apr;43(4):771-780. DOI:10.1038/s41401-021-00714-4
[2] V Bharath Kumar, et al. Sodium Danshensu Inhibits Oral Cancer Cell Migration and Invasion by Modulating p38 Signaling Pathway. Front Endocrinol (Lausanne). 2020 Sep 30:11:568436. DOI:10.3389/fendo.2020.568436
[3] Chen Yu, et al. Danshensu attenuates cisplatin-induced nephrotoxicity through activation of Nrf2 pathway and inhibition of NF-κB. Biomed Pharmacother. 2021 Oct:142:111995. DOI:10.1016/j.biopha.2021.111995 |
| | 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid Preparation Products And Raw materials |
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