Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]-

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Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- manufacturers
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Basic information
Product Name:Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]-
Synonyms:Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]-;c-Myc inhibitor 9
CAS:2799717-96-5
MF:C27H31N5OS
MW:473.63
EINECS:
Product Categories:
Mol File:2799717-96-5.mol
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Structure
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Chemical Properties
density 1.39±0.1 g/cm3(Predicted)
pka13.65±0.46(Predicted)
Safety Information
MSDS Information
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Usage And Synthesis
Usesc-Myc inhibitor 9 (compound 332) is a c-Myc inhibitor with an logEC50 of ≥6. c-Myc inhibitor 9 inhibits tumor growth in nude mouse models. c-Myc inhibitor 9 can be used for cancer research[1].
in vivo

c-Myc inhibitor 9 (3 mg/kg; i.p., twice a week for 49 days) effectively inhibits tumor growth in nude mice with A549 xenografts[1].

Animal Model:NMRI female nude mice with A549 xenografts[1]
Dosage:3 mg/kg
Administration:Intraperitoneal injection; 3 mg/kg, twice a week, for 49 days
Result:Reduced tumor volume.
References[1] Sheppard, David William, et al. Preparation of heteroaryl compounds as c-MYC mRNA translation modulators and uses thereof in the treatment of cancer. WO2022150316. 2022.
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- Preparation Products And Raw materials
Tag:Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]-(2799717-96-5) Related Product Information
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Fucoxanthin agrimol B RS47 Benzamide, 4-[[4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-N-[(1R,3R)-3-[(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)amino]cyclopentyl]-