N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide

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N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Suppliers list
Company Name: TargetMol Chemicals Inc.  
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Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.  
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Company Name: Shanghai Amole Biotechnology Co., Ltd.  
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N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide manufacturers

  • E235
  • E235 pictures
  • 2026-07-27
  • CAS:891894-69-2
  • Purity: 98.85%
  • Supply Ability: 10g
N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Basic information
Product Name:N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide
Synonyms:N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide;Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-(4-fluorophenyl)-N-[1-(phenylmethyl)-4-piperidinyl]-;E235
CAS:891894-69-2
MF:C28H25FN4OS
MW:484.59
EINECS:
Product Categories:
Mol File:891894-69-2.mol
N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Structure
N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Chemical Properties
density 1.35±0.1 g/cm3(Predicted)
pka13.10±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Usage And Synthesis
UsesE235 is an expression regulator of activates transcription factor 4 (ATF4). E235 reduces cell viability by activating integrated stress response (ISR) and DNA damage response signals. E235 has anti-proliferative activity and can be used for tumor research[1].
References[1] Sayers CM, et al. Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response. Mol Pharmacol. 2013 Mar;83(3):594-604. DOI:10.1124/mol.112.081810
N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide Preparation Products And Raw materials
Tag:N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide(891894-69-2) Related Product Information
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- N-(1-Benzylpiperidin-4-yl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]benzothiazole-6-carboxamide (S)-(-)-2-Azetidinecarboxylic acid 2H-Indol-2-one, 3-cycloheptyl-1,3-dihydro-3-(4-hydroxyphenyl)-6-Methoxy-7-Methyl-, (3S)- ISRIB eIF4A3-IN-2