(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid

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Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
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Company Name: TargetMol  
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Email: xuexiang.shao@tsbiochem.com
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid Basic information
Product Name:(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid
Synonyms:(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid;ZM 522
CAS:1454575-38-2
MF:C37H51FO4
MW:578.8
EINECS:
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Mol File:1454575-38-2.mol
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid Structure
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid Chemical Properties
Boiling point 630.1±35.0 °C(Predicted)
density 1.15±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
solubility DMF: 10 mg/ml
DMSO: 2 mg/ml
Ethanol: 2 mg/ml
pka4.60±0.70(Predicted)
Safety Information
MSDS Information
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid Usage And Synthesis
UsesZM522 is a CD73 inhibitor with an IC50 value of 0.56 μM. ZM522 effectively increases the levels of interferon-γ (INF-γ) and enhances immune activity by regulating the activation status of T cells. ZM522 holds promise for research in the fields of immunology and cancer therapy[1].
References[1] Zhang Y, et al. Application of a fluorine strategy in the lead optimization of betulinic acid to the discovery of potent CD73 inhibitors. Steroids. 2022 Dec;188:109112. DOI:10.1016/j.steroids.2022.109112
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid Preparation Products And Raw materials
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