ETIMIZOL
| 中文名称 | ETIMIZOL |
|---|---|
| 中文同义词 | 化合物ETIMIZOL;化合物:Etimizol CAS:64-99-3;Etimizol试剂;化合物：Etimizol CAS:64-99-3;Etimizol试剂;依替唑 |
| 英文名称 | Etimizol |
| 英文同义词 | Etimizol;Antiffine;Ethimizole;Ethymisol;Ethymisole;Ethymizol;Etimizole;Ethylnorantifein |
| CAS号 | 64-99-3 |
| 分子式 | C9H14N4O2 |
| 分子量 | 210.23 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 64-99-3.mol |
| 结构式 |  |
ETIMIZOL 性质
| 熔点 | 143-144℃ |
|---|---|
| 沸点 | 563.4±35.0 °C(Predicted) |
| 密度 | 1.26±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 乙醇：≥ 33.33 mg/mL (158.54 mM) |
| 形态 | 固体 |
| 酸度系数(pKa) | 14.22±0.46(Predicted) |
| 颜色 | 白色至米白色 |
The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3].