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Etimizol

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Etimizol manufacturers

  • Etimizol
  • Etimizol pictures
  • $44.00
  • 2026-09-10
  • CAS:64-99-3
  • Purity: 99.00%
  • Supply Ability: 10g
  • Etimizol
  • Etimizol pictures
  • $31.00
  • 2026-08-04
  • CAS:64-99-3
  • Purity: 99.00%
  • Supply Ability: 10g
Etimizol Basic information
Product Name:Etimizol
Synonyms:Etimizol;Antiffine;Ethimizole;Ethymisol;Ethymisole;Ethymizol;Etimizole;Ethylnorantifein
CAS:64-99-3
MF:C9H14N4O2
MW:210.23
EINECS:
Product Categories:
Mol File:64-99-3.mol
Etimizol Structure
Etimizol Chemical Properties
Melting point 143-144℃
Boiling point 563.4±35.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Ethanol: ≥ 33.33 mg/mL (158.54 mM)
form Solid
pka14.22±0.46(Predicted)
color White to off-white
Safety Information
MSDS Information
Etimizol Usage And Synthesis
UsesEtimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol can decrease the K-+ permeability of neurons' membrane during action potential.
in vivo

The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3].

References[1] Borisova GIu. Effect of etimizol on instrumental learning in rats. Biull Eksp Biol Med. 1985 Jun;99(6):705-6. PMID:4016262
[2] Trnovec T, et al. Etimizol absorption from the small intestine in dogs: the dependence on dosage. Biull Eksp Biol Med. 1986 Dec;102(12):729-30. PMID:3801627
[3] Vislobokov AI, et al. Elektrophysiological parameters of mollusk neurons under the influence of etimizol. Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(6):917-24. PMID:1132537
Etimizol Preparation Products And Raw materials
Tag:Etimizol(64-99-3) Related Product Information
Etimizol Antiphein 1H-Imidazole-4,5-dicarboxylic acid bis-methylamide Imidazole-4,5-dicarboxamide 1,5-Dimethyl-1H-imidazole-4-carbaldehyde BAPTA-AM