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T&W GROUP |
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5-Methoxyuridine manufacturers
- 5-Methoxyuridine
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- $47.00
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2026-07-14
- CAS:35542-01-9
- Purity: 99.43%
- Supply Ability: 10g
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| | 5-Methoxyuridine Basic information |
| Product Name: | 5-Methoxyuridine | | Synonyms: | mo(5)U;Uridine, 5-methoxy-;1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione;5 –Methoxyuridine,RNA anticodon nucleoside for RNA vaccines and geno mics,P2Y6 receptor agonist;5-MethoxyuridineA;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione;RNA-modified nucleoside mo5U;5-Methoxyuridine | | CAS: | 35542-01-9 | | MF: | C10H14N2O7 | | MW: | 274.23 | | EINECS: | 252-609-8 | | Product Categories: | Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides | | Mol File: | 35542-01-9.mol |  |
| | 5-Methoxyuridine Chemical Properties |
| density | 1.65±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | pka | 8+-.0.10(Predicted) | | form | Solid | | color | White to off-white | | λmax | 279 (pH 2)；277 (pH 12) | | InChI | InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1 | | InChIKey | ZXIATBNUWJBBGT-JXOAFFINSA-N | | SMILES | OC[C@H]1O[C@@H](N2C=C(OC)C(=O)NC2=O)[C@H](O)[C@@H]1O |
| WGK Germany | 3 | | HS Code | 29349990 |
| | 5-Methoxyuridine Usage And Synthesis |
| Description | 5-Methoxyuridine is an intermediate in the biosynthesis of pyrimidines and is also used as a precursor for other compounds. 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. It inhibits messenger RNA (mRNA) production in bacteria by interfering with sequence recognition and binding sites within the ribosome and preventing. | | Chemical Properties | Solid | | Uses | 5-Methoxyuridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. | | Definition | ChEBI: A derivative of uridine, bearing an additional methoxy substituent at position 5 on the uracil ring. | | Synthesis | 5-Hydroxyuridine was synthesized by the method described by T. Ueda. 5-Hydroxyuridine (30 mg) was further methylated by 20 y1 of dimethyl sulfate in 0.6 ml of 0.1 N NaOH. A reaction mixture was chromatographed on Whatman 3MM paper using solvent D. The band containing 5-Hydroxyuridine was extracted with water and the extract was further purified by paper chromatography in sol vent E. These procedures gave a 25% yield of mo5l). In addition to 5-Hydroxyuridine and the raw material, the methylated products contained 5% of 5-hydroxy-3-methyl uridine and 4% of 5-methoxy-3-methyluridine. |
| | 5-Methoxyuridine Preparation Products And Raw materials |
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