|
|
| | P9R (trifluoroacetate salt) Basic information |
| | P9R (trifluoroacetate salt) Chemical Properties |
| solubility | Water: Soluble |
| | P9R (trifluoroacetate salt) Usage And Synthesis |
| Description | P9R is a peptide with antiviral activity.1 It inhibits viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), SARS-CoV, influenza A subtypes H1N1 and H7N9, and rhinovirus in plaque reduction assays (IC50s = 0.9, 2.2, 4.2, 0.6, 0.9, and 5.7 µg/ml, respectively). In vivo, P9R (50 µg/animal three times over two days) increases survival and reduces H1N1 particle-forming units (PFUs) in the lungs to a similar extent as the influenza neuraminidase inhibitor zanamivir (Item No. 15123) in H1N1-infected mice.WARNING This product is not for human or veterinary use. | | References | [1] HANJUN ZHAO. A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2.[J]. ACS Combinatorial Science, 2020: 4252. DOI: 10.1038/s41467-020-17986-9 |
| | P9R (trifluoroacetate salt) Preparation Products And Raw materials |
|