达沙替尼杂质 基本信息
| 中文名称 | 达沙替尼杂质 |
|---|---|
| 中文同义词 | N-(2-羟基-6-甲基苯基)-2-((6-(4-(2-羟乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)氨基)噻唑-5-甲酰胺;2 -羟基- 2 DESCHLORO达沙替尼;2-去氯-2-羟基达沙替尼;2'-脱氯-2'-羟基达沙替尼;5-噻唑甲酰胺, 2-[[6-[4-(2-羟基乙基)-1-哌嗪基]-2-甲基-4-嘧啶基]氨基]-N-(2-羟基-6-甲基苯基)-;达沙替尼杂质 |
| 英文名称 | 2’-Deschloro-2’-hydroxy Dasatinib |
| 英文同义词 | 5-thiazolecarboxamide, 2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-n-(2-hydroxy-6-methylphenyl)-;N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide;2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-Methyl-4-pyriMidinyl]aMino]-N-(2-hydroxy-6-Methylphenyl;N-[2-Hydroxy-6-Methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-Methyl-4-pyriMidinyl]aMino]-5-thiazolecarboxaMide;N-(2-hydroxy-6-methylphenyl)-2-;2’-Deschloro-2’-hydroxy Dasatinib;N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide - [A7306] |
| CAS号 | 1159977-25-9 |
| 分子式 | C22H27N7O3S |
| 分子量 | 469.56 |
| EINECS号 | |
| 相关类别 | 杂质;杂质对照品;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Tyrosine Kinase Inhibitors;Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds, Tyrosine Kinase Inhibitors |
| Mol文件 | 1159977-25-9.mol |
| 结构式 |  |
达沙替尼杂质 性质
| 密度 | 1.410±0.06 g/cm3(Predicted) |
|---|---|
| 储存条件 | under inert gas (nitrogen or Argon) at 2–8 °C |
| 酸度系数(pKa) | 8.97±0.40(Predicted) |
| 外观 | light yellow solid |