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| | Chloroformamidine hydrochloride Basic information |
| Product Name: | Chloroformamidine hydrochloride | | Synonyms: | CHLOROFORMAMIDINE HYDROCHLORIDE;Chloroformamide hydrochloride;chloroformamidinium chloride;ChloroformamidineHCl;CARBAMIMIDIC ACID CHLORIDE HYDROCHLORIDE;CarbaMiMidic chloride, Monohydrochloride;Chloroformamidine hydrochloride 98%;ChloroforMaMidine hydrochloride, 98%+ | | CAS: | 29671-92-9 | | MF: | CH4Cl2N2 | | MW: | 114.96 | | EINECS: | 249-765-4 | | Product Categories: | | | Mol File: | 29671-92-9.mol |  |
| | Chloroformamidine hydrochloride Chemical Properties |
| Melting point | 180°C(lit.) | | density | 1.5592 (rough estimate) | | refractive index | 1.6300 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | color | White to Almost white | | InChI | InChI=1S/CH3ClN2.ClH/c2-1(3)4;/h(H3,3,4);1H | | InChIKey | FUQFHOLPJJETAP-UHFFFAOYSA-N | | SMILES | C(Cl)(=N)N.Cl |
| HazardClass | IRRITANT | | HS Code | 2925290090 |
| | Chloroformamidine hydrochloride Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Reactions | In efforts to optimize a manufacturing process for an internal development compound, a clean, efficient approach to guanidine synthesis using chloroformamidine hydrochloride was identified. The successful application of this chemistry to a variety of pyridines, anilines, and heterocyclic compounds highlights its use as an improved, alternative guanylation method for this often challenging set of aromatic amines.[1]
 | | Materials Uses | An interfacial molecular linker, chloroformamidine hydrochloride (CFA), is introduced to modify the properties of electron transport layers (ETLs) and modulate the interaction between the ETL and perovskite (PVK) layer via coordination/electrostatic coupling. It is found that the CFA molecular linker can passivate the oxygen vacancies/interfacial defects of SnO2 and construct an improved energetic alignment between the ETL and PVK layer. Moreover, unencapsulated PSCs based on CFA-modified SnO2 (CFA@SnO2) ETLs show enhanced thermal and moisture stability compared with PSCs without CFA modification.[2] | | Synthesis | Synthesis of chloroformamidine hydrochloride: cyanamide (50.0 g, 1.19 mol, 1 eq.) was dissolved in diethyl ether (900 ml) and the solution was cooled to 0°C. An ether solution of hydrogen chloride (450 g, 29%) was slowly added while the temperature was kept below +5 °C. After addition, the reaction mixture was continued to be stirred at room temperature for some time. Subsequently, the white precipitate was collected by filtration and dried under vacuum at 30 °C to afford a white solid product, chloroformamidine hydrochloride (132.66 g, 1.15 mol, 96.64% yield). | | References | [1] IAN ARMITAGE. The Use of Chloroformamidine Hydrochloride as a Reagent for the Synthesis of Guanidines from Electron Deficient Aromatic Amines[J]. Journal of Heterocyclic Chemistry, 2015, 54 1: 728-734. DOI:10.1002/jhet.2567.
[2] LI H, FU P, LU R, et al. Chloroformamidine hydrochloride as a molecular linker towards efficient and stable perovskite solar cells[J]. Journal of Materials Chemistry C, 2023, 15: 5039-5044. DOI:10.1039/D3TC00637A. |
| | Chloroformamidine hydrochloride Preparation Products And Raw materials |
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