Lyso-PAF C-18 -d4

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Lyso-PAF C-18 -d4 Suppliers list
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Lyso-PAF C-18 -d4 Basic information
Product Name:Lyso-PAF C-18 -d4
Synonyms:Lyso-PAF C-18 -d4
CAS:
MF:C26H52D4NO6P
MW:513.724348112
EINECS:
Product Categories:
Mol File:Mol File
Lyso-PAF C-18 -d4 Structure
Lyso-PAF C-18 -d4 Chemical Properties
solubility DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
Water: 20 mg/ml
Safety Information
MSDS Information
Lyso-PAF C-18 -d4 Usage And Synthesis
DescriptionLyso-PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of Lyso-PAF C-18 by GC- or LC-mass spectrometry. Lyso-PAF C-18 can be formed by either the action of PAF-AH on PAF C-18 or by the action of a CoA-independent transacylase on 1-O-octadecyl-2-acyl-glycerophosphocholine.1,2,3 Lyso PAF C-18 is a substrate for either PAF C-18 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.4,5WARNING This product is not for human or veterinary use.
References[1] D M STAFFORINI  L W T. Human plasma platelet-activating factor acetylhydrolase.[J]. Methods in molecular biology, 1999, 109: 49-58. DOI: 10.1385/1-59259-581-2:49
[2] Y. UEMURA F S T Lee. A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway.[J]. The Journal of Biological Chemistry, 1991, 50 1: 8268-8272. DOI: 10.1016/s0021-9258(18)92972-8
[3] M E VENABLE. Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophils.[J]. The Journal of Biological Chemistry, 1991, 266 28: 18691-18698.
[4] K DEGUCHI  A D  S Murashima. [Platelet activating factor].[J]. Nihon rinsho. Japanese journal of clinical medicine, 1987, 45 5: 1115-1126.
[5] M. VENABLE. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation.[J]. The Journal of Biological Chemistry, 1993, 49 1: 7965-7975. DOI: 10.1016/s0021-9258(18)53052-0
Lyso-PAF C-18 -d4 Preparation Products And Raw materials
Tag:Lyso-PAF C-18 -d4 Related Product Information
1-O-Hexadecyl-sn-glycero-3-phosphocholine 1-O-Octadecyl-sn-glycero-3-phosphocholine 1-O-Hexadecyl-(7,7,8,8-d4)-sn-glyceryl-3-phosphorylcholine PAF C-18-d4 1-O-Hexadecyl-(7,7,8,8-d4)-2-O-acetyl-sn-glyceryl-3-phosphorylcholine α-Ketoglutaric Acid-13C5