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| | 1-O-HEXADECYL-(7,7,8,8-D4)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Basic information |
| | 1-O-HEXADECYL-(7,7,8,8-D4)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml | | form | Liquid | | color | Colorless to light yellow | | Water Solubility | Water: 20 mg/ml |
| | 1-O-HEXADECYL-(7,7,8,8-D4)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Usage And Synthesis |
| Description | Lyso-PAF C-16-d4 contains four deuterium atoms at the 7, 7'', 8, and 8'' positions of the hexadecyl moiety. It is intended for use as an internal standard for the quantification of PAF C-16 by GC- or LC-mass spectrometry. Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16, or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine. Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase. | | Uses | Lyso-PAF C-16-d4 is the deuterium labeled Lyso-PAF C-16[1]. | | Definition | ChEBI: Lyso-PAF C-16-d4 is a monoalkylglycerophosphocholine. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110 |
| | 1-O-HEXADECYL-(7,7,8,8-D4)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE Preparation Products And Raw materials |
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