(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)

Request For Quotation
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Suppliers list
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Company Name: Chengdu Huachun Technology Co., Ltd  
Tel: 400-1166-196 15982826727
Email: cdhxsj@163.com
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774 400-920-5774
Email: sales@glpbio.cn
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Email: order@med-bio.cn
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Basic information
Product Name:(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
Synonyms:(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140;W140;W140 (TFA)
CAS:909725-64-0
MF:C18H28F3N2O6P
MW:456.4
EINECS:
Product Categories:
Mol File:909725-64-0.mol
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Structure
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Chemical Properties
storage temp. Store at -20°C
solubility Ethanol: 0.15 mg/ml
form A crystalline solid
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Usage And Synthesis
DescriptionW140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2
UsesW140 (TFA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
References1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor J. Neurophysiol. 108(5),1473-1483(2012).
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Preparation Products And Raw materials
Tag:(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)(909725-64-0) Related Product Information
N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride W-5 Hydrochloride N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride BenzenesulfonaMide, 4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]- W123 Exclusive [(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)