CALP3 manufacturers
- CALP3
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2026-08-04
- CAS:261969-05-5
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
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| Product Name: | CALP3 | | Synonyms: | CALP3;Calcium-like peptide 3;Calcium-Like Peptide 3,CALP-3;Calcium-Like Peptide 3 trifluoroacetate salt H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH trifluoroacetate salt;L-Lysine, L-valyl-L-lysyl-L-phenylalanylglycyl-L-valylglycyl-L-phenylalanyl-;CALP3 - Calcium like peptide 3 | | CAS: | 261969-05-5 | | MF: | C44H68N10O9 | | MW: | 881.07 | | EINECS: | | | Product Categories: | Calcium signaling | | Mol File: | 261969-05-5.mol |  |
| | CALP3 Chemical Properties |
| storage temp. | Desiccate at -20°C | | solubility | water, double-distilled: soluble | | form | Powder | | color | White to off-white | | Water Solubility | Soluble to 1 mg/ml in water |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | CALP3 Usage And Synthesis |
| Uses | CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia[1][2]. | | References | [1] Manion MK, et al. A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis. FASEB J. 2000 Jul;14(10):1297-306. DOI:10.1096/fj.14.10.1297
[2] Ferdek PE, et al. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides. Cell Death Dis. 2017 Mar 2;8(3):e2640. DOI:10.1038/cddis.2017.41 |
| | CALP3 Preparation Products And Raw materials |
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