|
|
| | Anti-connective tissue growth factor Basic information |
| Product Name: | Anti-connective tissue growth factor | | Synonyms: | Anti-CTGF antibody produced in rabbit;Anti-CTGF (center) antibody produced in rabbit;Anti-CTGF (C-term) antibody produced in rabbit;Anti-CTGF (181-195) antibody produced in rabbit;Anti-CCN2;Anti-IGFBP8;Anti-connective tissue growth factor;Anti-CTGF | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-connective tissue growth factor Structure]() |
| | Anti-connective tissue growth factor Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| | Anti-connective tissue growth factor Usage And Synthesis |
| Uses | Connective tissue growth factor (CTGF), a member of the CCN family of secreted matricellular proteins, regulates fibrosis, angiogenesis, cell proliferation, apoptosis, tumor growth, and metastasis. | | Biological Activity | CTGF (connective tissue growth factor) regulates cell communication with the extracellular matrix also inducing collagen deposition, stimulation and differentiation of mesenchymal cells and tissue remodeling. Abnormal expression of CTGF is associated with pathological conditions such as arthritis, fibrosis, and cancers. CTGF might control epithelial-mesenchymal transition, a signal pathway th at contains an important step associated with tumor cell metastasis, in many types of cancer. Overexpression of CTGF enhances esophageal squamous cell carcinoma by associating with TGF-β (transforming growth factor β) pathway. It is involved in the development of fibrotic tissues in different types of organs. Overexpression of CTGF leads to fibrosis in many disease condition. Overexpression of CTGF is observed in joint capsule during joint contracture. CTGF is associated with inflammation reactions and controls macrophage adhesion and migration. |
| | Anti-connective tissue growth factor Preparation Products And Raw materials |
|