- 4-Bromo-1H-imidazole
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- $999.00/ kg
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2026-04-03
- CAS:2302-25-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- 4-Bromoimidazole
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- $8.00 / 1KG
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2025-09-25
- CAS:2302-25-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 4-Bromo-1H-imidazole
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- $0.00 / 1KG
-
2022-01-27
- CAS:2302-25-2
- Min. Order: 1KG
- Purity: 99.4%
- Supply Ability: 100 tons
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| | 4-Bromo-1H-imidazole Basic information |
| | 4-Bromo-1H-imidazole Chemical Properties |
| Melting point | 131-135 °C (lit.) | | Boiling point | 324.7±15.0 °C(Predicted) | | density | 1.904±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | soluble in Dimethylformamide | | form | Crystalline Flakes or Powder | | pka | 11.70±0.10(Predicted) | | color | Colorless to beige | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C3H3BrN2/c4-3-1-5-2-6-3/h1-2H,(H,5,6) | | InChIKey | FHZALEJIENDROK-UHFFFAOYSA-N | | SMILES | C1NC(Br)=CN=1 | | CAS DataBase Reference | 2302-25-2(CAS DataBase Reference) |
| Hazard Codes | T | | Risk Statements | 25-36/37/38 | | Safety Statements | 26-36-45-37/39-28A | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | NI3517450 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | Ⅲ | | HS Code | 29339900 | | Storage Class | 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | | Toxicity | rat,LD50,oral,250mg/kg (250mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)GASTROINTESTINAL: OTHER CHANGES,Toxicology and Applied Pharmacology. Vol. 89, Pg. 175, 1987. |
| | 4-Bromo-1H-imidazole Usage And Synthesis |
| Chemical Properties | Colorless to beige crystalline flakes or powder | | Uses | Employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field | | General Description | 4-Bromo-1H-imidazole (4-Br-1H-Im) is a heterocyclic building block containing an imidazole ring. It crystallizes in the monoclinic space group P21/c. | | Synthesis | General procedure for the synthesis of 4-bromo-1H-imidazole from 2,4,5-tribromoimidazole: 2,4,5-tribromoimidazole (49 g, 161 mmol), sodium sulfite (101.5 g, 806 mmol), and water (500 mL) were added to a single-necked flask, and the reaction was stirred for 6 h at 110 °C. The reaction was carried out with the addition of ethyl acetate. After completion of the reaction, ethyl acetate was added for extraction, the organic layers were combined and dried with anhydrous sodium sulfate. The ethyl acetate was removed by concentration under reduced pressure to afford the target product 4-bromo-1H-imidazole (20.5 g, 89% yield). | | References | [1] Patent: CN106256830, 2016, A. Location in patent: Paragraph 0044; 0052; 0053; 0054
[2] Journal of the Chemical Society, 1922, vol. 121, p. 952
[3] Journal of the American Chemical Society, 2001, vol. 123, # 49, p. 12147 - 12151 |
| | 4-Bromo-1H-imidazole Preparation Products And Raw materials |
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